{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Neither of the two abstracts directly reports experimental or computational evidence regarding the function of LINC01365. In the first abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ", the authors develop a pipeline to investigate alterations in RNA secondary structure—so‐called riboSNitches—in noncoding regions, including long noncoding RNAs. Although several lncRNAs are highlighted as potentially acting as cancer drivers through effects on RNA processing, stability, localization, or translation, LINC01365 is not specifically mentioned. If it were implicated in that study, one might infer that, as a lncRNA, LINC01365 could influence oncogenic processes via changes in RNA structure and its downstream regulatory effects.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n The second abstract"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "reports on a genome‐wide association study for serum mineral elements, identifying genetic loci linked to copper concentration. Although a few lncRNA loci (e.g., those corresponding to LINC00908/LINC00683 and LINC01310) are reported, LINC01365 is not among the loci mentioned in relation to serum copper levels or other mineral elements.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Therefore, based on the available abstracts, there is no directly assigned function to LINC01365. However, from its classification as a long noncoding RNA and by analogy with the general roles of lncRNAs indicated in both studies, it could be hypothesized that if LINC01365 is ever found to participate in these processes, it might modulate RNA regulatory functions impacting cancer biology or other cellular pathways. Further dedicated studies would be necessary to define the precise biological role of LINC01365.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Funan He, Ran Wei, Zhan Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Integrative Analysis of Somatic Mutations in Non-coding Regions Altering RNA Secondary Structures in Cancer Genomes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-019-44489-5"}], "href": "https://doi.org/10.1038/s41598-019-44489-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31160636"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31160636"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Duojian Guo, Yu Zhou, Xingwei Wei, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Preliminary study of genome-wide association identifies novel susceptibility genes for serum mineral elements in the Chinese Han population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biol Trace Elem Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12011-021-02854-4"}], "href": "https://doi.org/10.1007/s12011-021-02854-4"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34417961"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34417961"}]}]}]}