{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n A recent study explored ambient‐temperature biobanking by lyophilizing unfractionated human cells, demonstrating that RNA species—including mRNAs, enhancer‐associated RNAs, and cancer biomarker long non‐coding RNAs—maintain their integrity after storage at room temperature for periods up to two months."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " In this context, LINC01374 is featured as one of the cancer‐associated long non‐coding RNAs whose abundance is preserved during lyophilization. Although the study primarily focused on the overall feasibility of preserving RNA quality under ambient conditions, the inclusion and stable detection of LINC01374 suggest that it may serve as a reliable cancer biomarker. This finding underscores the potential clinical and research utility of LINC01374 when employing novel biobanking approaches that avoid the limitations and costs of cryogenic storage (1).\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Lilla Ozgyin, Attila Horvath, Balint Laszlo Balint "}, {"type": "b", "children": [{"type": "t", "text": "Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.25764"}], "href": "https://doi.org/10.18632/oncotarget.25764"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30140372"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30140372"}]}]}]}