{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Recent studies have highlighted the pivotal role of long noncoding RNAs (lncRNAs) in the regulation of the tumor microenvironment and the cancer immunity response. In an investigation of bladder cancer (BLCA) using data from The Cancer Genome Atlas (TCGA), researchers identified an eight‐lncRNA signature with prognostic relevance and predictive capacity for immunotherapeutic response."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Among these, LINC01395 has been implicated as a key immune‐related regulator. Its expression is associated with the modulation of immune pathways that influence the infiltration and activity of immune cells within the BLCA microenvironment. Consequently, LINC01395 may serve not only as a prognostic biomarker but also as a potential target for immunotherapy, reflecting its contribution to the immune landscape of bladder cancer."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yucai Wu, Lei Zhang, Shiming He, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of immune-related LncRNA for predicting prognosis and immunotherapeutic response in bladder cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Aging (Albany NY) (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/aging.104115"}], "href": "https://doi.org/10.18632/aging.104115"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33221763"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33221763"}]}]}]}