{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Recent findings have begun to elucidate the role of the long intergenic non‐coding RNA LINC01448 in cancer biology. In particular, work detailed in"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "indicates that LINC01448 may function as a regulatory RNA that modulates gene expression and thereby contributes to key cellular processes. The study suggests that LINC01448 can affect tumor pathophysiology by influencing cell proliferation, migration, and invasion. Evidence points to a role for this lncRNA in acting as a molecular scaffold or competing endogenous RNA, thereby interacting with microRNAs and other gene regulatory elements to fine‐tune oncogenic signaling pathways. Such regulatory functions imply that abnormal expression of LINC01448 might be critical in the progression of cancer, positioning it as a potential biomarker and therapeutic target. Overall, these insights underscore the importance of LINC01448 in modulating the molecular mechanisms underlying tumor development and progression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Zhenglei Xu, Dingguo Zhang, Zhuliang Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MicroRNA-505, Suppressed by Oncogenic Long Non-coding RNA LINC01448, Acts as a Novel Suppressor of Glycolysis and Tumor Progression Through Inhibiting HK2 Expression in Pancreatic Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Cell Dev Biol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fcell.2020.625056"}], "href": "https://doi.org/10.3389/fcell.2020.625056"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33520999"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33520999"}]}]}]}