{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n LINC01537 is a long noncoding RNA that has emerged as a promising biomarker in lung cancer. In one study analyzing RNA sequencing data alongside TCGA datasets, LINC01537 was identified as the most significantly dysregulated lncRNA associated with lung cancer survival, suggesting its potential prognostic value in these patients."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In addition, LINC01537 was incorporated within a prognostic risk model based on ferroptosis‐related lncRNAs in lung adenocarcinoma, indicating that it may be involved in regulating cellular processes such as ferroptosis that can influence tumor progression. This association further highlights its potential as a therapeutic target and as a prognostic indicator in lung adenocarcinoma."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Together, these findings underscore the clinical relevance of LINC01537 in lung cancer, where its dysregulation appears to be linked with patient survival and may reflect its active role in key regulatory networks that control tumor cell fate.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Wei Gong, Lei Yang, Yuanyuan Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Analysis of Survival-Related lncRNA Landscape Identifies A Role for LINC01537 in Energy Metabolism and Lung Cancer Progression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms20153713"}], "href": "https://doi.org/10.3390/ijms20153713"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31374807"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31374807"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Lu Lu, Le-Ping Liu, Qiang-Qiang Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of a Ferroptosis-Related LncRNA Signature as a Novel Prognosis Model for Lung Adenocarcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Front Oncol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3389/fonc.2021.675545"}], "href": "https://doi.org/10.3389/fonc.2021.675545"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34249715"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34249715"}]}]}]}