{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n LINC01547 is a long non‐coding RNA that has recently emerged as a potential prognostic biomarker in ovarian cancer. In a comprehensive analysis of tumor tissues, LINC01547 was identified as one of 16 cancer‐specific lncRNAs within a co‐expression module that significantly correlated with clinical parameters—including overall patient survival—in ovarian cancer (see."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Although its precise molecular function remains to be fully elucidated, its inclusion in both competing endogenous RNA and RNA binding protein networks suggests that LINC01547 may be involved in mechanisms regulating tumorigenesis and disease progression. This finding complements other advances in biomedical research where transcriptomic biomarkers are increasingly being harnessed for noninvasive diagnostics and personalized medicine."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "2", "end_ref": "4"}]}, {"type": "t", "text": " While additional research is necessary to clarify its cellular localization and functional interactions—a focus that has proven critical for other biomolecules"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": "—the emerging role of LINC01547 underscores the potential of lncRNA-centered networks in refining prognostic models and therapeutic strategies in oncology.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Na Li, Xianquan Zhan "}, {"type": "b", "children": [{"type": "t", "text": "Identification of clinical trait-related lncRNA and mRNA biomarkers with weighted gene co-expression network analysis as useful tool for personalized medicine in ovarian cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EPMA J (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s13167-019-00175-0"}], "href": "https://doi.org/10.1007/s13167-019-00175-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31462944"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31462944"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Diana W Bianchi, Jill L Maron, Kirby L Johnson "}, {"type": "b", "children": [{"type": "t", "text": "Insights into fetal and neonatal development through analysis of cell-free RNA in body fluids."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Early Hum Dev (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.earlhumdev.2010.08.001"}], "href": "https://doi.org/10.1016/j.earlhumdev.2010.08.001"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20851538"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20851538"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Yuhui Hu, Hans Lehrach, Michal Janitz "}, {"type": "b", "children": [{"type": "t", "text": "Comparative analysis of an experimental subcellular protein localization assay and in silico prediction methods."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mol Histol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10735-009-9247-9"}], "href": "https://doi.org/10.1007/s10735-009-9247-9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20033263"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20033263"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "A Reymond, M Friedli, C N Henrichsen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genomics (2001)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1006/geno.2001.6640"}], "href": "https://doi.org/10.1006/geno.2001.6640"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11707072"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11707072"}]}]}]}