| Name | long intergenic non-protein coding RNA 1560 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Recent studies have uncovered a potential role for the long noncoding RNA LINC01560 in cancer through its association with competing endogenous RNA (ceRNA) mechanisms and prognostic biomarker signatures. In osteosarcoma, LINC01560 was found to be aberrantly expressed when comparing tumor and normal tissue profiles. Although its specific functional contribution within the ceRNA network remains to be fully elucidated, its differential expression alongside other lncRNAs suggests that LINC01560 may participate in the indirect regulation of mRNAs via microRNA sponging, thereby contributing to the molecular pathogenesis of osteosarcoma."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In colon adenocarcinoma, LINC01560 emerged as one of six independent prognostic lncRNA signatures associated with disease recurrence. Its identification within a prognostic prediction model indicates that LINC01560 might serve as a biomarker to distinguish recurrent from non-recurrent cases, and it may be involved in pathways related to glycan biosynthesis and colorectal cancer progression."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Ming Jiang, Yi-Ran Wang, Nan Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long noncoding RNA MEG3 play an important role in osteosarcoma development through sponging microRNAs."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.27791"}], "href": "https://doi.org/10.1002/jcb.27791"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30324678"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30324678"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Lipeng Jin, Chenyao Li, Tao Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A potential prognostic prediction model of colon adenocarcinoma with recurrence based on prognostic lncRNA signatures."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Genomics (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s40246-020-00270-8"}], "href": "https://doi.org/10.1186/s40246-020-00270-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32522293"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32522293"}]}]}]}
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| Synonyms | CXORF24 |
| Proteins | CX024_HUMAN |
| NCBI Gene ID | 203414 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LINC01560 has 884 functional associations with biological entities spanning 7 categories (molecular profile, organism, disease, phenotype or trait, chemical, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 18 datasets.
Click the + buttons to view associations for LINC01560 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of LINC01560 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of LINC01560 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of LINC01560 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of LINC01560 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| GEO Signatures of Differentially Expressed Genes for Diseases | disease perturbations changing expression of LINC01560 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of LINC01560 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations | transcription factor perturbations changing expression of LINC01560 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of LINC01560 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of LINC01560 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of LINC01560 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
| HPA Cell Line Gene Expression Profiles | cell lines with high or low expression of LINC01560 gene relative to other cell lines from the HPA Cell Line Gene Expression Profiles dataset. | |
| HPA Tissue Gene Expression Profiles | tissues with high or low expression of LINC01560 gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset. | |
| HPA Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of LINC01560 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LINC01560 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles | cell lines with high or low expression of LINC01560 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain LINC01560 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| Roadmap Epigenomics Cell and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of LINC01560 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue Gene Expression Profiles dataset. | |
| TISSUES Experimental Tissue Protein Expression Evidence Scores | tissues with high expression of LINC01560 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset. | |
