LINC01562 Gene

Name long intergenic non-protein coding RNA 1562
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Although the provided abstracts offer substantial insight into the roles of long non‐coding RNAs (lncRNAs) in processes including cell proliferation, extracellular matrix synthesis/degradation, apoptosis, and their involvement in intervertebral disc degeneration (IDD) and other pathologies such as multiple myeloma and breast cancer, none of these studies specifically examine or mention LINC01562. For instance, several studies focus on lncRNAs such as RP11‐296A18.3, which modulates nucleus pulposus cell proliferation and extracellular matrix synthesis by interacting with miR‑138 and influencing HIF1A expression in IDD"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ";"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": ";"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": ", while others investigate RMRP and other lncRNAs as key players in disc degeneration."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "4"}]}, {"type": "t", "text": " Additional works have broadly analyzed lncRNA–mRNA coexpression, ceRNA networks, and their contributions to degenerative processes"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "5"}]}, {"type": "t", "text": ";"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "6"}]}, {"type": "t", "text": ", as well as the clinical impact of lincRNAs in malignancies"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "7"}]}, {"type": "t", "text": ";"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "8"}]}, {"type": "t", "text": ";."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "9"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n In summary, while these abstracts underscore the importance of lncRNAs as regulators of key molecular pathways in disease, the function of LINC01562 is not described in any of them and remains to be elucidated. Further studies are needed to determine whether LINC01562 plays a similar regulatory role in processes such as cell proliferation, extracellular matrix modulation, and apoptosis in IDD or other pathological conditions.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xiaobin Wang, Guohua Lv, Jing Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LncRNA-RP11-296A18.3/miR-138/HIF1A Pathway Regulates the Proliferation ECM Synthesis of Human Nucleus Pulposus Cells (HNPCs)."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.26166"}], "href": "https://doi.org/10.1002/jcb.26166"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28543639"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28543639"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Zhong-Yuan Wan, Fang Song, Zhen Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Aberrantly expressed long noncoding RNAs in human intervertebral disc degeneration: a microarray related study."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arthritis Res Ther (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s13075-014-0465-5"}], "href": "https://doi.org/10.1186/s13075-014-0465-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25280944"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25280944"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Zheng Li, Xingye Li, Chong Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long non-coding RNAs in nucleus pulposus cell function and intervertebral disc degeneration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Prolif (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cpr.12483"}], "href": "https://doi.org/10.1111/cpr.12483"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30039593"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30039593"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Xuesong Wang, Lei Peng, Xiaojin Gong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LncRNA-RMRP promotes nucleus pulposus cell proliferation through regulating miR-206 expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Mol Med (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/jcmm.13817"}], "href": "https://doi.org/10.1111/jcmm.13817"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30156374"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30156374"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Yu Chen, Haijian Ni, Yingchuan Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Potential Role of lncRNAs in Contributing to Pathogenesis of Intervertebral Disc Degeneration Based on Microarray Data."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Med Sci Monit (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.12659/msm.894638"}], "href": "https://doi.org/10.12659/msm.894638"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26556537"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26556537"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Jinwen Zhu, Xinliang Zhang, Wenjie Gao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "lncRNA/circRNA‑miRNA‑mRNA ceRNA network in lumbar intervertebral disc degeneration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Med Rep (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/mmr.2019.10569"}], "href": "https://doi.org/10.3892/mmr.2019.10569"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31432173"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31432173"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Mehmet Kemal Samur, Stephane Minvielle, Annamaria Gulla, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Leukemia (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41375-018-0116-y"}], "href": "https://doi.org/10.1038/s41375-018-0116-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29749396"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29749396"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Rebecca S DeVaux, Jason I Herschkowitz "}, {"type": "b", "children": [{"type": "t", "text": "Beyond DNA: the Role of Epigenetics in the Premalignant Progression of Breast Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mammary Gland Biol Neoplasia (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10911-018-9414-2"}], "href": "https://doi.org/10.1007/s10911-018-9414-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30306389"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30306389"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Wen-Kang Chen, Xiao-Hua Yu, Wei Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "lncRNAs: novel players in intervertebral disc degeneration and osteoarthritis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Prolif (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cpr.12313"}], "href": "https://doi.org/10.1111/cpr.12313"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27859817"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27859817"}]}]}]}
NCBI Gene ID 104054213
API
Download Associations
Predicted Functions View LINC01562's ARCHS4 Predicted Functions.
Co-expressed Genes View LINC01562's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View LINC01562's ARCHS4 Predicted Functions.

Functional Associations

LINC01562 has 0 functional associations with biological entities spanning 0 categories () extracted from 0 datasets.

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Dataset Summary