{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n Genome-wide association analyses in Mexican‐Mestizo postmenopausal women have implicated the long noncoding RNA LINC01563 in bone mineral density (BMD) regulation (1). Although its precise molecular function remains to be fully defined, genetic variations within or near LINC01563 have been associated with variations in BMD measured at critical skeletal sites such as the femoral neck and lumbar spine, suggesting a potential regulatory role in bone metabolism (1). As a noncoding RNA, LINC01563 may be involved in modulating the expression of genes that regulate osteoblast differentiation, bone remodeling, and overall skeletal homeostasis. These findings highlight LINC01563 as a promising candidate for further functional studies, which could elucidate its mechanistic contributions to bone health and its potential as a therapeutic target in managing osteoporosis (1)."}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Marisela Villalobos-Comparán, Rogelio F Jiménez-Ortega, Karol Estrada, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Genomics (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2017/5831020"}], "href": "https://doi.org/10.1155/2017/5831020"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28840121"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28840121"}]}]}]}