{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nLINC02875 has emerged as a crucial long noncoding RNA in hepatocellular carcinoma (HCC), where its elevated expression is linked to adverse clinical characteristics and reduced overall survival, particularly in HBV-related cases. Investigations have revealed that LINC02875 promotes key oncogenic behaviors in HCC cells, including enhanced proliferation, migration, and invasion, while its knockdown significantly impairs these processes. Mechanistically, LINC02875 appears to exert its effects partly through modulation of miR-485-5p, positioning this lncRNA as both a prognostic biomarker and a promising therapeutic target in HCC management."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yujian Liu, Jingrui Yang, Rui-Sheng Ke, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LINC02875 Upregulation Contributed to Poor Prognosis for the Hepatocellular Carcinoma and Progression for the Cancerous Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Horm Metab Res (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1055/a-1913-8223"}], "href": "https://doi.org/10.1055/a-1913-8223"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36055279"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36055279"}]}]}]}