LOC105378220 Gene

Name	macrophage receptor MARCO-like
Description	Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to be active in collagen-containing extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Mar 2025]
Synonyms	MARCOL
NCBI Gene ID	105378220
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

LOC105378220 has 1,105 functional associations with biological entities spanning 5 categories (functional term, phrase or reference, disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets.

Click the + buttons to view associations for LOC105378220 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

LOC105378220 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of LOC105378220 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing LOC105378220 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with LOC105378220 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with LOC105378220 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	GO Biological Process Annotations 2023	biological processes involving LOC105378220 gene from the curated GO Biological Process Annotations 2023 dataset.
	JASPAR Predicted Human Transcription Factor Targets 2025	transcription factors regulating expression of LOC105378220 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
	JASPAR Predicted Mouse Transcription Factor Targets 2025	transcription factors regulating expression of LOC105378220 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of LOC105378220 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	PFOCR Pathway Figure Associations 2024	pathways involving LOC105378220 protein from the Wikipathways PFOCR 2024 dataset.
	Rummagene Transcription Factor Associations 2026	transcription factors regulating expression of LOC105378220 gene from the Rummagene Transcription Factor Associations 2026 dataset.
	RummaGEO Drug Perturbation Signatures	drug perturbations changing expression of LOC105378220 gene from the RummaGEO Drug Perturbation Signatures dataset.
	RummaGEO Gene Perturbation Signatures	gene perturbations changing expression of LOC105378220 gene from the RummaGEO Gene Perturbation Signatures dataset.
	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	drug perturbations changing expression of LOC105378220 gene from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	tissues with high expression of LOC105378220 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	tissues co-occuring with LOC105378220 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.