| Name | general transcription factor II, i pseudogene |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n In the study on asbestos‐related squamous cell lung carcinoma (ARLC‐SCC)"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ", a comprehensive analysis was performed to identify differentially expressed genes and candidate biomarkers associated with asbestos‐related lung cancer. Although the investigation detailed 1,333 differentially expressed genes and highlighted several key “cross‐talk” genes (such as EGFR, PRKX, PDGFB, PIK3R3, SLK, IGF1, CDC42, and PRKCA) that bridge multiple ARLC‐SCC‐specific pathways, the functional role of LOC642929 was not explicitly characterized in the reported analyses. As such, LOC642929 appears among the differentially expressed gene set without an assigned specific function in the context of the pathways examined. The available data suggest that while LOC642929 is part of the molecular landscape of ARLC‐SCC, its biological role remains undefined based on this study, emphasizing the need for further investigations to clarify whether it might contribute to disease mechanisms or serve as an ancillary biomarker.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Jiang Du, Lin Zhang "}, {"type": "b", "children": [{"type": "t", "text": "Pathway deviation-based biomarker and multi-effect target identification in asbestos-related squamous cell carcinoma of the lung."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Med (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3892/ijmm.2017.2878"}], "href": "https://doi.org/10.3892/ijmm.2017.2878"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28204826"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28204826"}]}]}]}
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| NCBI Gene ID | 642929 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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LOC642929 has 436 functional associations with biological entities spanning 4 categories (molecular profile, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 11 datasets.
Click the + buttons to view associations for LOC642929 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of LOC642929 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of LOC642929 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of LOC642929 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of LOC642929 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of LOC642929 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of LOC642929 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of LOC642929 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of LOC642929 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of LOC642929 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain LOC642929 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of LOC642929 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |