| Name | leucine rich repeat containing 51 |
| Description | This gene belongs to the leucine-rich repeat containing family. The encoded protein contains a transmembrane domain and two leucine-rich repeat domains. Unlike in mouse and other mammals, readthrough transcription is observed in primates between this gene and the adjacent transmembrane O-methyltransferase (Tomt) gene. Previously, this locus was annotated as a single gene representing the readthrough transcripts as well as the two different transcript species that encoded different proteins. It has since been split into three genes, including the two stand-alone genes and a third gene representing the readthrough transcription. [provided by RefSeq, Feb 2022] |
| NCBI Gene ID | 120356739 |
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| Expression in Tissues and Cell Lines |
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LRRC51 has 616 functional associations with biological entities spanning 3 categories (chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 9 datasets.
Click the + buttons to view associations for LRRC51 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CM4AI KOLF21J CRISPRi Gene Perturbation Atlas | gene perturbations changing expression of LRRC51 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by LRRC51 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| GTEx Tissue-Specific Aging Signatures | tissue samples with high or low expression of LRRC51 gene relative to other tissue samples from the GTEx Tissue-Specific Aging Signatures dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of LRRC51 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Mouse Transcription Factor Targets 2025 | transcription factors regulating expression of LRRC51 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of LRRC51 gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of LRRC51 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of LRRC51 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| Tahoe Therapeutics Tahoe 100M Perturbation Atlas | drug perturbations changing expression of LRRC51 gene from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. | |
