MAGI2-IT1 Gene

Name MAGI2 intronic transcript 1
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\n The collection of studies provided spans a broad range of topics—from the development of genetic tools for bacterial pathogens and the molecular mechanisms regulating viral particle assembly to the standardization of gene nomenclature for non‐coding RNAs and investigations in membrane organization, reproductive outcomes, and viral glycoprotein processing."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "11"}]}, {"type": "t", "text": "\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Although one of these abstracts focuses on the naming and standardized classification of human non‐protein coding RNA genes"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "3"}]}, {"type": "t", "text": ", none of the studies directly address the function of the long noncoding RNA MAGI2‑IT1. As a member of the growing class of lncRNAs, MAGI2‑IT1 is catalogued within efforts to assign unique gene symbols and names to non‐coding transcripts, yet its functional role has not been elucidated in these reports. In other words, while the literature increasingly appreciates the regulatory potential of lncRNAs and some studies have begun to explore mechanisms by which non‐coding transcripts influence gene expression and cellular function, the specific biological activities and mechanistic contributions of MAGI2‑IT1 remain uncharacterized in the present body of work.\n "}]}, {"type": "t", "text": "\n "}, {"type": "p", "children": [{"type": "t", "text": "\n Future investigations that directly examine MAGI2‑IT1 will be required to determine whether it plays a role in transcriptional regulation, signal transduction, chromatin organization, or other cellular processes. At this time, the available abstracts do not provide evidence to assign a clear functional profile to MAGI2‑IT1.\n "}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Andrew M Staroscik, David W Hunnicutt, Kate E Archibald, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Development of methods for the genetic manipulation of Flavobacterium columnare."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Microbiol (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1471-2180-8-115"}], "href": "https://doi.org/10.1186/1471-2180-8-115"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18620586"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18620586"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Sandrina Dafonseca, Pascale Coric, Bernard Gay, et al. 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Synonyms MAGI2-IT, PR47, MAGI2IT1, MAGI2IT
NCBI Gene ID 266671
API
Download Associations
Predicted Functions View MAGI2-IT1's ARCHS4 Predicted Functions.
Co-expressed Genes View MAGI2-IT1's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View MAGI2-IT1's ARCHS4 Predicted Functions.

Functional Associations

MAGI2-IT1 has 13 functional associations with biological entities spanning 2 categories (cell line, cell type or tissue, gene, protein or microRNA) extracted from 3 datasets.

Click the + buttons to view associations for MAGI2-IT1 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of MAGI2-IT1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of MAGI2-IT1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of MAGI2-IT1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.