MIMT1 Gene

Name MER1 repeat containing imprinted transcript 1 (non-protein coding)
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRecent high-throughput profiling of colorectal cancer has revealed that the long noncoding RNA MER1 Repeat Containing Imprinted Transcript 1 (MIMT1) is significantly down-regulated in tumor tissues compared with adjacent normal tissues. This downregulation suggests that MIMT1 may act as a tumor suppressor by contributing to the proper regulation of noncoding RNA networks, which in turn influence the expression and function of genes involved in colorectal cancer progression. Although the mechanistic details remain to be fully elucidated, the loss of normal MIMT1 expression appears to be a factor in the dysregulation of cellular processes that ordinarily counteract tumorigenesis, thereby opening avenues for further research into its role in cancer signaling pathways."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Faramarz Vejdandoust, Rahmaneh Moosavi, Nasrin Fattahi Dolatabadi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MIMT1 and LINC01550 are uncharted lncRNAs down-regulated in colorectal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Exp Pathol (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/iep.12467"}], "href": "https://doi.org/10.1111/iep.12467"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36727289"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36727289"}]}]}]}
Synonyms LINC00067, MIM1, NCRNA00067
NCBI Gene ID 100073347
API
Download Associations
Predicted Functions View MIMT1's ARCHS4 Predicted Functions.
Co-expressed Genes View MIMT1's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View MIMT1's ARCHS4 Predicted Functions.

Functional Associations

MIMT1 has 815 functional associations with biological entities spanning 4 categories (molecular profile, disease, phenotype or trait, cell line, cell type or tissue, gene, protein or microRNA) extracted from 18 datasets.

Click the + buttons to view associations for MIMT1 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of MIMT1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
ChEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of MIMT1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
ChEA Transcription Factor Targets transcription factors binding the promoter of MIMT1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of MIMT1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
dbGAP Gene-Trait Associations traits associated with MIMT1 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
ENCODE Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at MIMT1 gene from the ENCODE Histone Modification Site Profiles dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of MIMT1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of MIMT1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of MIMT1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Sample Gene Expression Profiles tissue samples with high or low expression of MIMT1 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
Hub Proteins Protein-Protein Interactions interacting hub proteins for MIMT1 from the curated Hub Proteins Protein-Protein Interactions dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of MIMT1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of MIMT1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
KnockTF Gene Expression Profiles with Transcription Factor Perturbations transcription factor perturbations changing expression of MIMT1 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of MIMT1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles cell types and tissues with high or low DNA methylation of MIMT1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
Roadmap Epigenomics Histone Modification Site Profiles histone modification site profiles with high histone modification abundance at MIMT1 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
TCGA Signatures of Differentially Expressed Genes for Tumors tissue samples with high or low expression of MIMT1 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.