{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRecent investigations into recurrent implantation failure (RIF) in Korean women undergoing in vitro fertilization have highlighted the potential regulatory role of MIR1302-3. In one study, the miR‑1302‑3C>T polymorphism was evaluated among several miRNA variants and found to be significantly associated with a decreased incidence of RIF, suggesting that the T allele may confer a protective effect during embryo implantation. Furthermore, allele combination analysis—particularly the pairing of miR‑938 with miR‑1302‑3—supported these findings, while interaction analysis indicated that the miR‑1302‑3CC genotype, when coupled with certain coagulation profiles (i.e., activated partial thromboplastin time levels), might influence the prevalence of RIF. Together, these data suggest that MIR1302-3 may modulate key cellular processes central to endometrial receptivity and implantation success."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Hyun Ah Lee, Eun Hee Ahn, Hyo Geun Jang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association Between miR-605A>G, miR-608G>C, miR-631I>D, miR-938C>T, and miR-1302-3C>T Polymorphisms and Risk of Recurrent Implantation Failure."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Reprod Sci (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/1933719118773413"}], "href": "https://doi.org/10.1177/1933719118773413"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29739285"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29739285"}]}]}]}