|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
|NCBI Gene ID
|Expression in Tissues and Cell Lines
MIR302C has 403 functional associations with biological entities spanning 5 categories (molecular profile, disease, phenotype or trait, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 11 datasets.
Click the + buttons to view associations for MIR302C from the datasets below.
If available, associations are ranked by standardized value
|CCLE Cell Line Gene CNV Profiles
|cell lines with high or low copy number of MIR302C gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
|CTD Gene-Disease Associations
|diseases associated with MIR302C gene/protein from the curated CTD Gene-Disease Associations dataset.
|ENCODE Histone Modification Site Profiles
|histone modification site profiles with high histone modification abundance at MIR302C gene from the ENCODE Histone Modification Site Profiles dataset.
|ENCODE Transcription Factor Binding Site Profiles
|transcription factor binding site profiles with transcription factor binding evidence at the promoter of MIR302C gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
|ENCODE Transcription Factor Targets
|transcription factors binding the promoter of MIR302C gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
|GeneRIF Biological Term Annotations
|biological terms co-occuring with MIR302C gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
|GeneSigDB Published Gene Signatures
|PubMedIDs of publications reporting gene signatures containing MIR302C from the GeneSigDB Published Gene Signatures dataset.
|JASPAR Predicted Transcription Factor Targets
|transcription factors regulating expression of MIR302C gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
|Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles
|cell lines with high or low copy number of MIR302C gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
|KnockTF Gene Expression Profiles with Transcription Factor Perturbations
|transcription factor perturbations changing expression of MIR302C gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
|Roadmap Epigenomics Histone Modification Site Profiles
|histone modification site profiles with high histone modification abundance at MIR302C gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.