{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRecent investigations into the roles of microRNAs in disease pathogenesis have highlighted MIR3202-2 as a key regulatory molecule. In primary Sjögren's syndrome, aberrant expression of MIR3202-2 is implicated in modulating microRNA–mRNA networks that impact lymphocyte infiltration, ultimately contributing to exocrine gland dysfunction and epithelial injury. These findings suggest that MIR3202-2 may serve both as an indicator of disease activity and as a potential target for therapeutic intervention."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nSimilarly, in the context of bronchopulmonary dysplasia (BPD) in preterm infants, there is emerging evidence that MIR3202-2 also participates in the molecular mechanisms underlying alveolar dysplasia and impaired lung function. Its regulatory influence on key mRNA targets may contribute to the pathogenesis of BPD, offering new insights into diagnostic markers and strategies for improved disease management."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Qi Gao, Zhuang Ye, Tao Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hsa-miR-3202 attenuates Jurkat cell infiltration via MMP2 in primary Sjögren's syndrome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Oral Pathol Med (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/jop.13355"}], "href": "https://doi.org/10.1111/jop.13355"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36076347"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36076347"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Li-Chun Zeng, Shu-Hui Zhang, Na Fu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "miR-3202 inhibits bronchopulmonary dysplasia-mediated apoptosis and oxidative stress in bronchial epithelial cells via targeting RAG1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Res Pract (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.prp.2024.155482"}], "href": "https://doi.org/10.1016/j.prp.2024.155482"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "39067173"}], "href": "https://pubmed.ncbi.nlm.nih.gov/39067173"}]}]}]}