{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRecent investigations suggest that microRNA MIR3910-2 may play a role in regulating key tumor‐suppressive pathways in hepatocellular carcinoma (HCC), potentially through modulation of MST1 expression. Previous work has shown that specific depletion of MST1 in a mouse model of liver‐driven HCC enhances tumor development; however, the mechanisms controlling MST1 levels remain largely elusive."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": " Based on its nature as a regulatory RNA, MIR3910-2 is hypothesized to contribute to the fine-tuning of MST1 expression via post-transcriptional mechanisms, thereby influencing critical cellular processes such as apoptosis and proliferation that are central to HCC progression. Although direct experimental evidence for MIR3910-2’s function in this context remains to be established, its prospective involvement underscores the importance of further studies aimed at deciphering the molecular circuitry governing MST1 regulation in liver cancer.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Lina Cheng, Hongwei Wang, Shuangyin Han "}, {"type": "b", "children": [{"type": "t", "text": "MiR-3910 Promotes the Growth and Migration of Cancer Cells in the Progression of Hepatocellular Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dig Dis Sci (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10620-017-4670-3"}], "href": "https://doi.org/10.1007/s10620-017-4670-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28823082"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28823082"}]}]}]}