{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRecent studies on microRNA expression in human diseases have begun to implicate MIR5571 as a candidate molecular marker. In synovial tissue from patients with rheumatoid arthritis, high‐throughput RNA sequencing identified several dysregulated miRNAs, among which MIR5571 showed altered expression patterns suggestive of a role in modulating the inflammatory response and possibly serving as a biomarker for disease diagnosis and monitoring."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn a separate study investigating microRNA profiles in lung adenocarcinoma, screening for miRNAs related to prognosis revealed that MIR5571 may be differentially expressed in tumor tissue. Although the exact molecular mechanisms remain to be fully defined, its altered expression in lung adenocarcinoma suggests that MIR5571 could be involved in regulating tumorigenesis‐related pathways and holds potential as a prognostic indicator."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "2"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Cailong Liu, Axiao Pan, Xiaowei Chen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MiR-5571-3p and miR-135b-5p, derived from analyses of microRNA profile sequencing, correlate with increased disease risk and activity of rheumatoid arthritis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Rheumatol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10067-018-04417-w"}], "href": "https://doi.org/10.1007/s10067-018-04417-w"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30707326"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30707326"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Wei Wang, Bin Liu, Xiaoran Duan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of Three Differentially Expressed miRNAs as Potential Biomarkers for Lung Adenocarcinoma Prognosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Comb Chem High Throughput Screen (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2174/1386207323666200124123103"}], "href": "https://doi.org/10.2174/1386207323666200124123103"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31976830"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31976830"}]}]}]}