| HGNC Family | Non-coding RNAs |
| Name | microRNA 6088 |
| Description | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe abstract available from the study (PubMed:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "focuses on elucidating the role of long noncoding RNA MEG3 in the progression of glioma and its underlying mechanisms, emphasizing the broader impact of noncoding RNAs in tumorigenesis. However, there is no mention or functional characterization of MIR6088 within this work. Consequently, while the investigation provides valuable insights into MEG3‐mediated oncogenic processes, it does not offer any information regarding the function of MIR6088. \n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xin Gong, Meng-Yi Huang "}, {"type": "b", "children": [{"type": "t", "text": "Tumor-Suppressive Function of lncRNA-MEG3 in Glioma Cells by Regulating miR-6088/SMARCB1 Axis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomed Res Int (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1155/2020/4309161"}], "href": "https://doi.org/10.1155/2020/4309161"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32420340"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32420340"}]}]}]}
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| Synonyms | HSA-MIR-6088 |
| NCBI Gene ID | 102464836 |
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| Predicted Functions |
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MIR6088 has 0 functional associations with biological entities spanning 0 categories () extracted from 0 datasets.
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| Dataset | Summary |
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