| HGNC Family | Non-coding RNAs |
| Name | microRNA 6765 |
| Description | microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe study characterized a mouse brain-specific gene, msvop, which is the ortholog of Xenopus synaptic vesicle-2-associated protein (svop). This gene is expressed predominantly in neuronal cells—most notably within the hippocampus and cerebellum—and its protein product localizes to the cytosol, suggesting a role in neuronal gene regulation and synaptic function. It is important to note, however, that this abstract (PubMed PMID:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "does not mention or contain any information regarding MIR6765, and therefore no functional insights for MIR6765 can be derived from this source.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Eun Young Cho, Chae Jin Lee, Keun Su Son, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Characterization of mouse synaptic vesicle-2-associated protein (Msvop) specifically expressed in the mouse central nervous system."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gene (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.gene.2008.10.008"}], "href": "https://doi.org/10.1016/j.gene.2008.10.008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19013223"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19013223"}]}]}]}
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| Synonyms | HSA-MIR-6765 |
| NCBI Gene ID | 102465458 |
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| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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MIR6765 has 0 functional associations with biological entities spanning 0 categories () extracted from 0 datasets.
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If available, associations are ranked by standardized value
| Dataset | Summary |
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