{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nA careful review of the provided abstracts reveals that none of these studies mention or characterize MIR6770‐2. Instead, the articles focus overwhelmingly on the role of gap junction proteins—most notably connexin26 (Cx26) and connexin30 (Cx30)—in processes such as cochlear development, auditory function, and cell–cell communication in both neural and epithelial tissues. These papers describe how mutations or deletions in connexin‐encoding genes underlie various forms of hereditary deafness, disrupt postnatal maturation of the organ of Corti, or even alter skin differentiation. However, no explicit functional data, expression profile, or regulatory mechanism regarding MIR6770‐2 is provided in any of the cited works."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "22"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn summary, while the extensive literature here provides significant insights into connexin‐mediated gap junction communication and its relevance to auditory and epidermal physiology—and ultimately to pathological conditions such as nonsyndromic deafness and keratitis‐ichthyosis‐deafness syndrome—it does not address any role for MIR6770‐2. Consequently, the function and potential biological roles of MIR6770‐2 remain undetermined within the context of these abstracts, and additional focused studies would be necessary to elucidate any contributions of MIR6770‐2 in these or other cellular systems."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "22"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "M R Deans, D L Paul "}, {"type": "b", "children": [{"type": "t", "text": "Mouse horizontal cells do not express connexin26 or connexin36."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Commun Adhes (2001)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3109/15419060109080754"}], "href": "https://doi.org/10.3109/15419060109080754"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12064619"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12064619"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Martine Cohen-Salmon, Thomas Ott, Vincent Michel, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Curr Biol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0960-9822(02)00904-1"}], "href": "https://doi.org/10.1016/s0960-9822(02"}, {"type": "t", "text": "00904-1) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12121617"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12121617"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Shoab Ahmad, Shanping Chen, Jianjun Sun, et al. 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