{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nDespite an extensive examination of placental vascular remodeling, trophoblast differentiation, and tumor-derived exosome functions in the provided studies, none of the abstracts (available under PubMed IDs"}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": "mention or characterize MIR6805. While the first two abstracts detail intricate aspects of maternal-fetal vascular interfacing and trophoblast lineage dynamics in the mouse placenta, and the third abstract focuses on the role of tumor-derived exosomal circ_0064516 in cervical cancer angiogenesis, none address any functional role, expression pattern, or regulatory mechanism for MIR6805.\n"}]}, {"type": "t", "text": "\n \n"}, {"type": "p", "children": [{"type": "t", "text": "\nThus, based on the current set of publications, the function of MIR6805 remains unannotated and is not implicated in the processes of placental vascular development, trophoblast subtype specification, or cancer-related angiogenesis. Further targeted studies would be required to determine whether MIR6805 has any regulatory or functional impact in these biological contexts.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "S Lee Adamson, Yong Lu, Kathie J Whiteley, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Interactions between trophoblast cells and the maternal and fetal circulation in the mouse placenta."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dev Biol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0012-1606(02)90773-6"}], "href": "https://doi.org/10.1016/s0012-1606(02"}, {"type": "t", "text": "90773-6) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12376109"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12376109"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Dong Hu, James C Cross "}, {"type": "b", "children": [{"type": "t", "text": "Ablation of Tpbpa-positive trophoblast precursors leads to defects in maternal spiral artery remodeling in the mouse placenta."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dev Biol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ydbio.2011.07.036"}], "href": "https://doi.org/10.1016/j.ydbio.2011.07.036"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21839735"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21839735"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Yujue Wang, Yao Xie, Xue Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Tumor cells-derived extracellular vesicles carry circ_0064516 competitively inhibit microRNA-6805-3p and promote cervical cancer angiogenesis and tumor growth."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Expert Opin Ther Targets (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/14728222.2024.2306353"}], "href": "https://doi.org/10.1080/14728222.2024.2306353"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38270096"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38270096"}]}]}]}