{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nIn a recent study on hypertrophic scarring (HS), integrated RNA sequencing analysis revealed that among the many differentially expressed RNAs involved in the pathology of HS, hsa‐miR‑6884‑5p (MIR6884) emerged as a key component of a competing endogenous RNA (ceRNA) regulatory network. Specifically, MIR6884 was found to interact with the long noncoding RNA MEG3 and target the mRNA for ADAMTS14, a gene implicated in extracellular matrix remodeling. This interaction suggests that MIR6884 may play an important role in modulating the expression of genes involved in collagen deposition and extracellular matrix organization—two processes that are central to the formation of hypertrophic scars."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xiaodong Li, Zeliang He, Julei Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS Open Bio (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/2211-5463.13167"}], "href": "https://doi.org/10.1002/2211-5463.13167"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33932142"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33932142"}]}]}]}