{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe study (PMID:"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "describes the creation of a novel Cre transgenic mouse, where a compound promoter—comprising elements of the SV40 small t antigen and mouse alpha‐amylase‐2 sequences—drives early, broad expression of the recombinase in the embryonic endoderm. This expression is evident prior to the outgrowth of the pancreas and lungs, except in key regions such as the liver and ventral pancreas. The selective activity of the promoter highlights intrinsic transcriptional differences between dorsal and ventral pancreatic primordia as well as the presence of an anterior endodermal domain, which appears refractory to this chimerical promoter. Notably, however, the abstract does not mention or address the function of MIR7111, and therefore no conclusions regarding this microRNA’s role can be drawn from the present study."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Liliana Kockel, Alessandra Strom, Alexandra Delacour, et al. "}, {"type": "b", "children": [{"type": "t", "text": "An amylase/Cre transgene marks the whole endoderm but the primordia of liver and ventral pancreas."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genesis (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/dvg.20206"}], "href": "https://doi.org/10.1002/dvg.20206"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16786601"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16786601"}]}]}]}