{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe collection of abstracts provided offers extensive insight into the diverse roles of acid‐sensing ion channels (ASICs) in neuronal and non‐neuronal tissues. They describe how various ASIC subunits coassemble to mediate proton‐gated currents in models ranging from dorsal root ganglion and hippocampal neurons to cochlear hair cells and vascular smooth muscle, and how these channels contribute to processes such as mechanotransduction, pain perception, synaptic plasticity, and the regulation of vascular tone (for example."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "5"}]}, {"type": "t", "text": " Additional studies document ASIC regulation by intracellular signaling molecules and interactions with scaffolding proteins that affect their surface expression and function in both central and peripheral neurons."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "6", "end_ref": "8"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nOther abstracts extend these findings to reveal ASIC contributions in visual transduction, inflammatory pain, drug-related behavior, and even aspects of myogenic constriction and protective vascular responses, emphasizing the subunit-specific impacts and the wide-ranging physiological and pathological roles of these channels."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "9", "end_ref": "13"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nNotably, while a subset of these studies even touches upon regulatory mechanisms that may involve miRNA‐mediated modulation of ASIC expression"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "14"}]}, {"type": "t", "text": ", none of the abstracts mention or provide any data regarding MIR7150. In short, although these papers present a comprehensive picture of ASIC functions and their regulation in various systems, there is no information available about a role for MIR7150 in any of the described contexts."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "15"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Christopher J Benson, Jinghui Xie, John A Wemmie, et al. 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