{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe abstract provided (1) does not mention or address MIR8065. Instead, it focuses on the function of Cep85, a centrosomal protein that binds to the Nek2A isoform. Cep85 localizes to the centrosomes by forming a granule meshwork around the proximal ends of centrioles and plays a critical role in controlling centrosome disjunction; it is able to restrict Nek2A kinase activity both in vitro and in the cellular context when partnered with PP1γ. The work thus implicates Cep85 as an antagonist of Nek2A activity, maintaining proper centrosomal cohesion during interphase and preventing premature centrosome separation."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Canhe Chen, Fang Tian, Lin Lu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.171637"}], "href": "https://doi.org/10.1242/jcs.171637"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26220856"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26220856"}]}]}]}