MXD1 Gene

HGNC Family	MAX dimerization proteins (MXD), Basic helix-loop-helix proteins (BHLH)
Name	MAX dimerization protein 1
Description	This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nMXD1, a member of the Myc/Max/Mad transcription factor network, functions as a transcriptional repressor that antagonizes c‐Myc–mediated gene activation by dimerizing with MAX and binding canonical E‐box DNA sequences. Structural studies have revealed that Mad–Max heterodimer formation exhibits distinct coiled‐coil and leucine‐zipper interactions compared to Myc–Max complexes, thereby defining its ability to modulate promoter occupancy and regulate programs of cell proliferation versus differentiation, including the control of rDNA transcription and ribosome biogenesis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "3"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nThe transcriptional repressive activity and stability of MXD1 are finely adjusted by multiple regulatory mechanisms. Post‐translational modifications—such as phosphorylation by kinases downstream of growth factor signaling—reduce MXD1’s binding affinity to target promoters, thus alleviating its inhibitory effect on c‐Myc–driven transcription. In addition, several microRNAs (for example, miR‑19a/b, miR‑202, and miR‑382‑5p) directly target MXD1’s mRNA, thereby disrupting feedback loops between c‐Myc and MXD1 that normally enforce cell cycle arrest, differentiation or senescence. Furthermore, protein–protein interactions with partners such as TCP10L also stabilize MXD1, enhancing its ability to arrest cell cycle progression."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "4", "end_ref": "11"}]}, {"type": "t", "text": ""}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its classical role in counteracting c‐Myc–dependent transcription, MXD1 localizes to the nucleolus where it appears to regulate ribosomal RNA synthesis and, by extension, ribosome biogenesis. This function contributes to overall control of cell growth, while altered MXD1 expression has been associated with tumor suppression in diverse malignancies – including chronic myeloid leukemia, esophageal squamous cell carcinoma and breast cancer – and with modulation of cytokine expression in virally infected cells. These findings support the concept that MXD1 functions as an important molecular hub; its loss or dysregulation through genetic mutation or microRNA-mediated downregulation may tip the balance in favor of oncogenic and pro-survival pathways."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "17"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Mikhail A Nikiforov, Nikita Popov, Iulia Kotenko, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Mad and Myc basic domains are functionally equivalent."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M212298200"}], "href": "https://doi.org/10.1074/jbc.M212298200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12538578"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12538578"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Satish K Nair, Stephen K Burley "}, {"type": "b", "children": [{"type": "t", "text": "X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0092-8674(02)01284-9"}], "href": "https://doi.org/10.1016/s0092-8674(02"}, {"type": "t", "text": "01284-9) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12553908"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12553908"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Gretchen Poortinga, Katherine M Hannan, Hayley Snelling, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO J (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.emboj.7600335"}], "href": "https://doi.org/10.1038/sj.emboj.7600335"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15282543"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15282543"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Xiao-Ling Guo, Ling Pan, Xue-Jun Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression and mutation analysis of genes that encode the Myc antagonists Mad1, Mxi1 and Rox in acute leukaemia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Leuk Lymphoma (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/10428190701342018"}], "href": "https://doi.org/10.1080/10428190701342018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17577784"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17577784"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Kan Jiang, Nadine Hein, Kolja Eckert, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Regulation of the MAD1 promoter by G-CSF."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucleic Acids Res (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/nar/gkn002"}], "href": "https://doi.org/10.1093/nar/gkn002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18203738"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18203738"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Jidong Zhu, John Blenis, Junying Yuan "}, {"type": "b", "children": [{"type": "t", "text": "Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0802785105"}], "href": "https://doi.org/10.1073/pnas.0802785105"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18451027"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18451027"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Siqin Wu, Anne Hultquist, Per Hydbring, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TGF-beta enforces senescence in Myc-transformed hematopoietic tumor cells through induction of Mad1 and repression of Myc activity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2009.09.009"}], "href": "https://doi.org/10.1016/j.yexcr.2009.09.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19766114"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19766114"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Q Wu, Z Yang, Y An, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MiR-19a/b modulate the metastasis of gastric cancer cells by targeting the tumour suppressor MXD1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Dis (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/cddis.2014.110"}], "href": "https://doi.org/10.1038/cddis.2014.110"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24675462"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24675462"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Lulu Farhana, Marcia I Dawson, Joseph A Fontana "}, {"type": "b", "children": [{"type": "t", "text": "Down regulation of miR-202 modulates Mxd1 and Sin3A repressor complexes to induce apoptosis of pancreatic cancer cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Biol Ther (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4161/15384047.2014.987070"}], "href": "https://doi.org/10.4161/15384047.2014.987070"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25611699"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25611699"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Suqin Shen, Jie Zuo, Huan Feng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMB Rep (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.5483/bmbrep.2016.49.6.248"}], "href": "https://doi.org/10.5483/bmbrep.2016.49.6.248"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26698869"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26698869"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Roberta Zini, Chiara Rossi, Ruggiero Norfo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "miR-382-5p Controls Hematopoietic Stem Cell Differentiation Through the Downregulation of MXD1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Stem Cells Dev (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/scd.2016.0150"}], "href": "https://doi.org/10.1089/scd.2016.0150"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27520398"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27520398"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Datong Zheng, Weiling Wu, Na Dong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mxd1 mediates hypoxia-induced cisplatin resistance in osteosarcoma cells by repression of the PTEN tumor suppressor gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Carcinog (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/mc.22676"}], "href": "https://doi.org/10.1002/mc.22676"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28543796"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28543796"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Chen Huan, Lou Jin, Wang Heng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MXD1 regulates the imatinib resistance of chronic myeloid leukemia cells by repressing BCR-ABL1 expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Leuk Res (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.leukres.2018.10.012"}], "href": "https://doi.org/10.1016/j.leukres.2018.10.012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30419548"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30419548"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Xiliang Zhang, Huibin Zhao, Yuxing Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The MicroRNA-382-5p/MXD1 Axis Relates to Breast Cancer Progression and Promotes Cell Malignant Phenotypes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Surg Res (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jss.2019.09.018"}], "href": "https://doi.org/10.1016/j.jss.2019.09.018"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31635836"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31635836"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Howard C H Yim, Thomas Y Y Leon, James C B Li "}, {"type": "b", "children": [{"type": "t", "text": "MXD1 regulates the H9N2 and H1N1 influenza A virus-induced chemokine expression and their replications in human macrophage."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Leukoc Biol (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/JLB.4MA0620-703RR"}], "href": "https://doi.org/10.1002/JLB.4MA0620-703RR"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32794336"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32794336"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Shu Li, Xin He, Yichao Gan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Targeting miR-21 with NL101 blocks c-Myc/Mxd1 loop and inhibits the growth of B cell lymphoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Theranostics (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7150/thno.53561"}], "href": "https://doi.org/10.7150/thno.53561"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33537096"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33537096"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Feng Du, Dezuo Dong, Xiaodong Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MXD1 is a Potential Prognostic Biomarker and Correlated With Specific Molecular Change and Tumor Microenvironment Feature in Esophageal Squamous Cell Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Technol Cancer Res Treat (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/15330338211052142"}], "href": "https://doi.org/10.1177/15330338211052142"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34761715"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34761715"}]}]}]}
Synonyms	MAD1, BHLHC58
Proteins	MAD1_HUMAN
NCBI Gene ID	4084
API
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MXD1 has 8,441 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 121 datasets.

Click the + buttons to view associations for MXD1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

MXD1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MXD1 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of MXD1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of MXD1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of MXD1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of MXD1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MXD1 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	Biocarta Pathways	pathways involving MXD1 protein from the Biocarta Pathways dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of MXD1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MXD1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MXD1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of MXD1 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of MXD1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of MXD1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with MXD1 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MXD1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of MXD1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of MXD1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of MXD1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of MXD1 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing MXD1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing MXD1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing MXD1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing MXD1 protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with MXD1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with MXD1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing MXD1 protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of MXD1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with MXD1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with MXD1 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with MXD1 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by MXD1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with MXD1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with MXD1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with MXD1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with MXD1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with MXD1 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at MXD1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MXD1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of MXD1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing MXD1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.