MYRF Gene

Name	myelin regulatory factor
Description	This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nMYRF (Myelin Regulatory Factor) is a membrane‐bound transcription factor that plays a pivotal role in central nervous system myelination. Synthesized in the endoplasmic reticulum, MYRF undergoes an unusual intramolecular auto‐proteolytic cleavage mediated by a chaperone domain evolutionarily related to bacteriophage tailspike proteins. This processing releases an N‐terminal fragment that assembles into a stable homo‐trimer, enabling specific recognition of novel DNA motifs and thereby initiating transcription of key myelin genes. In demyelinated models, MYRF expression in newly generated oligodendrocytes is essential for their transition from a premyelinating to a myelinating state, underscoring its critical function in remyelination."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "5"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its role in myelination, MYRF has emerged as a key developmental regulator in multiple organ systems. Genetic studies have implicated de novo and inherited damaging variants in MYRF in a spectrum of congenital anomalies—including congenital diaphragmatic hernia, congenital heart defects, and genitourinary malformations—that together define a novel syndrome encompassing disorders of sex development. Moreover, MYRF mutations have been identified in patients with nanophthalmos, linking its transcriptional dysfunction to aberrant embryonic development of critical tissues. These findings from human exome and whole‐genome sequencing, as well as supportive animal models, highlight the broader pleiotropic functions of MYRF in organogenesis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "6", "end_ref": "12"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn the context of ocular development and other specialized tissues, truncating mutations in the C‐terminal region of MYRF have been shown to cause autosomal dominant high hyperopia and nanophthalmos—with consequent risks of angle-closure glaucoma—as well as retinal pigment epithelium abnormalities and degeneration. Additionally, studies in pancreatic ductal adenocarcinoma indicate that MYRF supports endoplasmic reticulum homeostasis in highly secretory cells, while preliminary genetic association analyses have explored potential links between MYRF variants and athletic performance through its influence on myelination. Together, these diverse studies underscore the pleiotropic nature of MYRF, illuminating its fundamental roles in neurobiology, ocular development, secretory cell function, and congenital human disorders."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "13", "end_ref": "18"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Zhihua Li, Yungki Park, Edward M Marcotte "}, {"type": "b", "children": [{"type": "t", "text": "A Bacteriophage tailspike domain promotes self-cleavage of a human membrane-bound transcription factor, the myelin regulatory factor MYRF."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Biol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pbio.1001624"}], "href": "https://doi.org/10.1371/journal.pbio.1001624"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23966832"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23966832"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Dongkyeong Kim, Jin-Ok Choi, Chuandong Fan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucleic Acids Res (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/nar/gkx080"}], "href": "https://doi.org/10.1093/nar/gkx080"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28160598"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28160598"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Greg J Duncan, Jason R Plemel, Peggy Assinck, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Myelin regulatory factor drives remyelination in multiple sclerosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Acta Neuropathol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00401-017-1741-7"}], "href": "https://doi.org/10.1007/s00401-017-1741-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28631093"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28631093"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Chuandong Fan, Hongjoo An, Mohamed Sharif, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Functional mechanisms of MYRF DNA-binding domain mutations implicated in birth defects."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jbc.2021.100612"}], "href": "https://doi.org/10.1016/j.jbc.2021.100612"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33798553"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33798553"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Hongjoo An, Chuandong Fan, Mohamed Sharif, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-020-57593-8"}], "href": "https://doi.org/10.1038/s41598-020-57593-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31964908"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31964908"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Hongjian Qi, Lan Yu, Xueya Zhou, et al. "}, {"type": "b", "children": [{"type": "t", "text": "De novo variants in congenital diaphragmatic hernia identify MYRF as a new syndrome and reveal genetic overlaps with other developmental disorders."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Genet (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pgen.1007822"}], "href": "https://doi.org/10.1371/journal.pgen.1007822"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30532227"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30532227"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Sarah J Garnai, Michelle L Brinkmeier, Ben Emery, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS Genet (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pgen.1008130"}], "href": "https://doi.org/10.1371/journal.pgen.1008130"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31048900"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31048900"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Linda Z Rossetti, Kevin Glinton, Bo Yuan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Review of the phenotypic spectrum associated with haploinsufficiency of MYRF."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Med Genet A (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ajmg.a.61182"}], "href": "https://doi.org/10.1002/ajmg.a.61182"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31069960"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31069960"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Hailey Pinz, Louise C Pyle, Dong Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "De novo variants in Myelin regulatory factor (MYRF) as candidates of a new syndrome of cardiac and urogenital anomalies."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Med Genet A (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ajmg.a.38620"}], "href": "https://doi.org/10.1002/ajmg.a.38620"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29446546"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29446546"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Kohei Hamanaka, Atsushi Takata, Yuri Uchiyama, et al. "}, {"type": "b", "children": [{"type": "t", "text": "MYRF haploinsufficiency causes 46,XY and 46,XX disorders of sex development: bioinformatics consideration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/ddz066"}], "href": "https://doi.org/10.1093/hmg/ddz066"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30985895"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30985895"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Katerina Slaba, Marta Jezova, Petra Pokorna, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Two sisters with cardiac-urogenital syndrome secondary to pathogenic splicing variant in the MYRF gene with unaffected parents: A case of gonadal mosaicism?"}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Genet Genomic Med (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/mgg3.2139"}], "href": "https://doi.org/10.1002/mgg3.2139"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36695166"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36695166"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Owen M Siggs, Emmanuelle Souzeau, James Breen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Autosomal dominant nanophthalmos and high hyperopia associated with a C-terminal frameshift variant in "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "MYRF"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": "."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Vis (2019)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31700225"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31700225"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Owen M Siggs, Mona S Awadalla, Emmanuelle Souzeau, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The genetic and clinical landscape of nanophthalmos and posterior microphthalmos in an Australian cohort."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Genet (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/cge.13722"}], "href": "https://doi.org/10.1111/cge.13722"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32052405"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32052405"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Marta Milan, Chiara Balestrieri, Gabriele Alfarano, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dev Cell (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.devcel.2020.09.011"}], "href": "https://doi.org/10.1016/j.devcel.2020.09.011"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32997974"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32997974"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Xueshan Xiao, Wenmin Sun, Jiamin Ouyang, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Truncation mutations in MYRF underlie primary angle closure glaucoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Genet (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00439-022-02487-0"}], "href": "https://doi.org/10.1007/s00439-022-02487-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36129575"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36129575"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Xiaowei Yu, Nannan Sun, Congcong Guo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Evaluation of "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "MYRF"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " as a candidate gene for primary angle closure glaucoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Vis (2021)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35136345"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35136345"}]}]}]}
Synonyms	MMERV, PQN-47, NDT80, 11orf9, C11ORF9, MRF
Proteins	MRF_HUMAN
NCBI Gene ID	745
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

MYRF has 7,491 functional associations with biological entities spanning 8 categories (molecular profile, chemical, disease, phenotype or trait, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 116 datasets.

Click the + buttons to view associations for MYRF from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

MYRF Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MYRF gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of MYRF gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of MYRF gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of MYRF gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of MYRF gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of MYRF gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of MYRF gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MYRF gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of MYRF gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of MYRF gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of MYRF gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of MYRF gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with MYRF gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MYRF gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of MYRF gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of MYRF gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with MYRF gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	CM4AI U2OS Cell Map Protein Localization Assemblies	assemblies containing MYRF protein from integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of MYRF gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing MYRF protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing MYRF protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores	cellular components containing MYRF protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.
	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	cellular components containing MYRF protein in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with MYRF protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with MYRF protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with MYRF gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with MYRF gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with MYRF gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of MYRF protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by MYRF gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with MYRF gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with MYRF gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with MYRF gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with MYRF gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with MYRF gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at MYRF gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of MYRF gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of MYRF gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing MYRF from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with MYRF gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.