ND4L Gene

Name NADH dehydrogenase subunit 4L
Description Enables NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrion. Part of mitochondrial inner membrane and respiratory chain complex I. Implicated in Leber hereditary optic neuropathy and diabetes mellitus. [provided by Alliance of Genome Resources, Mar 2025]
NCBI Gene ID 4539
API
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Predicted Functions View ND4L's ARCHS4 Predicted Functions.
Co-expressed Genes View ND4L's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View ND4L's ARCHS4 Predicted Functions.

Functional Associations

ND4L has 151 functional associations with biological entities spanning 4 categories (chemical, functional term, phrase or reference, cell line, cell type or tissue, gene, protein or microRNA) extracted from 6 datasets.

Click the + buttons to view associations for ND4L from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of ND4L gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
DGIdb Drug Targets 2026 interacting drugs for ND4L protein from the DGIdb Drug Targets 2026 dataset.
KEGG Pathways 2026 pathways involving ND4L protein from the KEGG Pathways 2026 dataset.
PFOCR Pathway Figure Associations 2024 pathways involving ND4L protein from the Wikipathways PFOCR 2024 dataset.
Rummagene Transcription Factor Associations 2026 transcription factors regulating expression of ND4L gene from the Rummagene Transcription Factor Associations 2026 dataset.
WikiPathways Pathways 2024 pathways involving ND4L protein from the WikiPathways Pathways 2024 dataset.