NID2 Gene

Name	nidogen 2 (osteonidogen)
Description	This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane.[provided by RefSeq, Jun 2010]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nA growing body of evidence indicates that epigenetic silencing of NID2 is a common event in a variety of human cancers. In oral squamous cell carcinoma, bladder cancer, lung cancer, gastric cancer, nasopharyngeal carcinoma, and glioma, promoter hypermethylation leads to reduced NID2 expression, which correlates with increased tumor cell proliferation, migration, metastasis, and ultimately poorer clinical outcomes. Moreover, re‐expression or demethylation of NID2 has been shown to suppress clonogenic survival and metastatic behaviors, while its aberrant methylation in bodily fluids (saliva, urine) serves as a sensitive diagnostic biomarker for early cancer detection."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "10"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBesides its role in tumor suppression, NID2 is a critical component of the basement membrane where it functions as a linker protein, bridging the laminin and collagen IV networks. This structural role is vital for basement membrane deposition, stabilization, and the maintenance of tissue architecture during embryonic development. Research also suggests that NID2 can compensate for the loss of nidogen-1, ensuring proper extracellular matrix assembly, while proteolytic processing by enzymes such as ADAMTS1 can modulate vascular remodeling in the tumor microenvironment."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "15"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its functions in extracellular matrix integrity and tumor suppression, NID2 appears to play a regulatory role in cellular differentiation processes. For instance, in the context of osteoarthritis, NID2 influences chondrogenic differentiation by up-regulating SOX9 and modulating RUNX2 expression in chondrogenic progenitor cells. Altered expression levels of NID2 have also been associated with hepatocellular, ovarian, and colon carcinomas, supporting its emerging role as both a diagnostic/prognostic biomarker and a multifunctional regulator within the tumor microenvironment."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "16", "end_ref": "19"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "R Guerrero-Preston, E Soudry, J Acero, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Prev Res (Phila) (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/1940-6207.CAPR-11-0006"}], "href": "https://doi.org/10.1158/1940-6207.CAPR-11-0006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21558411"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21558411"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Zeynep Yegin, Sezgin Gunes, Recep Buyukalpelli "}, {"type": "b", "children": [{"type": "t", "text": "Hypermethylation of TWIST1 and NID2 in tumor tissues and voided urine in urinary bladder cancer patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "DNA Cell Biol (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/dna.2013.2030"}], "href": "https://doi.org/10.1089/dna.2013.2030"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23682613"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23682613"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Joseph J Fantony, Thomas A Longo, Ajay Gopalakrishna, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Urinary NID2 and TWIST1 methylation to augment conventional urine cytology for the detection of bladder cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cancer Biomark (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3233/CBM-160261"}], "href": "https://doi.org/10.3233/CBM-160261"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28106542"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28106542"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Annie Wai Yeeng Chai, Arthur Kwok Leung Cheung, Wei Dai, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Metastasis-suppressing NID2, an epigenetically-silenced gene, in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.12889"}], "href": "https://doi.org/10.18632/oncotarget.12889"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27793011"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27793011"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Jianfeng Wang, Yan Zhao, Hongyan Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Silencing NID2 by DNA Hypermethylation Promotes Lung Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Oncol Res (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12253-019-00609-0"}], "href": "https://doi.org/10.1007/s12253-019-00609-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30826972"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30826972"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Zhi-Hao Yu, Yue-Mei Wang, Yu-Zhang Jiang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NID2 can serve as a potential prognosis prediction biomarker and promotes the invasion and migration of gastric cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Pathol Res Pract (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.prp.2019.152553"}], "href": "https://doi.org/10.1016/j.prp.2019.152553"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31362888"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31362888"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Ratakorn Srisuttee, Areeya Arayataweegool, Patnarin Mahattanasakul, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Evaluation of NID2 promoter methylation for screening of Oral squamous cell carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "BMC Cancer (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/s12885-020-6692-z"}], "href": "https://doi.org/10.1186/s12885-020-6692-z"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32171289"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32171289"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Zexing Shan, Wentao Wang, Yilin Tong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Genome-Scale Analysis Identified NID2, SPARC, and MFAP2 as Prognosis Markers of Overall Survival in Gastric Cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Med Sci Monit (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.12659/MSM.929558"}], "href": "https://doi.org/10.12659/MSM.929558"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33758160"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33758160"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Xu Feng, Xiaoyong Xie, Baoshi Zheng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The more potential performance of nidogen 2 methylation by tissue or plasma DNA over brichoalveolar lavage DNA in diagnosis of nonsmall cell lung cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cancer Res Ther (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.4103/0973-1482.235352"}], "href": "https://doi.org/10.4103/0973-1482.235352"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29970687"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29970687"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Jie Hao, Congmei Huang, Weiwei Zhao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association of NID2 SNPs with Glioma Risk and Prognosis in the Chinese Population."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuromolecular Med (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12017-024-08795-0"}], "href": "https://doi.org/10.1007/s12017-024-08795-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38935278"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38935278"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Nicolai Miosge, Takako Sasaki, Rupert Timpl "}, {"type": "b", "children": [{"type": "t", "text": "Evidence of nidogen-2 compensation for nidogen-1 deficiency in transgenic mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Matrix Biol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0945-053x(02)00070-7"}], "href": "https://doi.org/10.1016/s0945-053x(02"}, {"type": "t", "text": "00070-7) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12475645"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12475645"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Linda Ulazzi, Silvia Sabbioni, Elena Miotto, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cancer (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1186/1476-4598-6-17"}], "href": "https://doi.org/10.1186/1476-4598-6-17"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17328794"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17328794"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Roswitha Nischt, Cathrine Schmidt, Nicolae Mirancea, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Lack of nidogen-1 and -2 prevents basement membrane assembly in skin-organotypic coculture."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Invest Dermatol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/sj.jid.5700562"}], "href": "https://doi.org/10.1038/sj.jid.5700562"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17008882"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17008882"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Estefanía Martino-Echarri, Rubén Fernández-Rodríguez, Francisco Javier Rodríguez-Baena, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Cancer (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/ijc.28271"}], "href": "https://doi.org/10.1002/ijc.28271"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23681936"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23681936"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "N Miosge, S Holzhausen, C Zelent, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Nidogen-1 and nidogen-2 are found in basement membranes during human embryonic development."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Histochem J (2001)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1023/a:1014995523521"}], "href": "https://doi.org/10.1023/a:1014995523521"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12005023"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12005023"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Boris Schminke, Jenny Frese, Christa Bode, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Clinical significance of decreased nidogen-2 expression in the tumor tissue and serum of patients with hepatocellular carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Surg Oncol (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jso.22047"}], "href": "https://doi.org/10.1002/jso.22047"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21815147"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21815147"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Annie Wai Yeeng Chai, Arthur Kwok Leung Cheung, Wei Dai, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Nidogen-2: A new biomarker in colon cancer patients."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Ann Ital Chir (2022)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34593672"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34593672"}]}]}]}
Synonyms	NID-2
Proteins	NID2_HUMAN
NCBI Gene ID	22795
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

NID2 has 8,090 functional associations with biological entities spanning 9 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 118 datasets.

Click the + buttons to view associations for NID2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

NID2 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of NID2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of NID2 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of NID2 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of NID2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of NID2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of NID2 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of NID2 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of NID2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of NID2 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of NID2 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of NID2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of NID2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with NID2 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with NID2 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of NID2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of NID2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of NID2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of NID2 gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing NID2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing NID2 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with NID2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with NID2 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of NID2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with NID2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with NID2 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with NID2 gene/protein from the curated CTD Gene-Disease Associations dataset.
	dbGAP Gene-Trait Associations	traits associated with NID2 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by NID2 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with NID2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with NID2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with NID2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with NID2 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with NID2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with NID2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at NID2 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of NID2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of NID2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing NID2 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD Gene-Disease Associations	diseases associated with NID2 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with NID2 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.