OFCC1 Gene

Name	orofacial cleft 1 candidate 1
Synonyms	Opo, MRDS1
Proteins	OFCC1_HUMAN
NCBI Gene ID	266553
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

OFCC1 has 472 functional associations with biological entities spanning 7 categories (molecular profile, organism, disease, phenotype or trait, functional term, phrase or reference, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 39 datasets.

Click the + buttons to view associations for OFCC1 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

OFCC1 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of OFCC1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of OFCC1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of OFCC1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of OFCC1 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of OFCC1 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of OFCC1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of OFCC1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with OFCC1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	dbGAP Gene-Trait Associations	traits associated with OFCC1 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores	diseases associated with OFCC1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with OFCC1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at OFCC1 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of OFCC1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	GAD Gene-Disease Associations	diseases associated with OFCC1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
	GAD High Level Gene-Disease Associations	diseases associated with OFCC1 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with OFCC1 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GEO Signatures of Differentially Expressed Genes for Diseases	disease perturbations changing expression of OFCC1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of OFCC1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of OFCC1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of OFCC1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of OFCC1 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Viral Infections	virus perturbations changing expression of OFCC1 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of OFCC1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GWAS Catalog SNP-Phenotype Associations	phenotypes associated with OFCC1 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.
	GWASdb SNP-Disease Associations	diseases associated with OFCC1 gene in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.
	GWASdb SNP-Phenotype Associations	phenotypes associated with OFCC1 gene in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.
	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	cell lines with high or low expression of OFCC1 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
	HPA Tissue Protein Expression Profiles	tissues with high or low expression of OFCC1 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
	HuGE Navigator Gene-Phenotype Associations	phenotypes associated with OFCC1 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
	IMPC Knockout Mouse Phenotypes	phenotypes of mice caused by OFCC1 gene knockout from the IMPC Knockout Mouse Phenotypes dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of OFCC1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	LOCATE Predicted Protein Localization Annotations	cellular components predicted to contain OFCC1 protein from the LOCATE Predicted Protein Localization Annotations dataset.
	MGI Mouse Phenotype Associations 2023	phenotypes of transgenic mice caused by OFCC1 gene mutations from the MGI Mouse Phenotype Associations 2023 dataset.
	MiRTarBase microRNA Targets	microRNAs targeting OFCC1 gene in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of OFCC1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	Pathway Commons Protein-Protein Interactions	interacting proteins for OFCC1 from the Pathway Commons Protein-Protein Interactions dataset.
	PFOCR Pathway Figure Associations 2023	pathways involving OFCC1 protein from the PFOCR Pathway Figure Associations 2023 dataset.
	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	cell types and tissues with high or low DNA methylation of OFCC1 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
	TISSUES Experimental Tissue Protein Expression Evidence Scores	tissues with high expression of OFCC1 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset.