OR2AP1 Gene

HGNC Family G protein-coupled receptors
Name olfactory receptor, family 2, subfamily AP, member 1
Description Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nA review of the provided abstracts reveals that none contain any mention or data regarding OR2AP1. The studies instead focus on the synthesis, modification, processing, and assembly of zona pellucida glycoproteins (ZP1, ZP2, and ZP3), which form the extracellular coat of mammalian oocytes, mediate sperm‐egg recognition, and regulate fertilization‐associated events. These works detail extensive co‑ and post‑translational modifications, including glycosylation and disulfide bond formation, which are critical for proper folding, secretion, and incorporation of the ZP proteins into a functional matrix."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "5"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nOther abstracts examine the mechanisms that regulate ZP protein polymerization and extracellular matrix assembly. They describe critical elements such as conserved hydrophobic patches and proprotein convertase cleavage sites that prevent premature intracellular oligomerization, ensuring that only properly processed glycoproteins are incorporated into the zona pellucida. In addition, studies using site‐directed mutagenesis and fusion constructs highlight the importance of specific protein domains and their modifications in mediating sperm binding and triggering the acrosomal reaction."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "6", "end_ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nFurther contributions describe downstream events during fertilization, including signaling cascades that facilitate the acrosome reaction and the subsequent hardening of the zona pellucida to block polyspermy. Detailed insights into the intracellular trafficking, post-fertilization processing, and spatial organization of the ZP proteins in the oocyte environment are provided. Such work underscores the multifaceted roles of zona pellucida components not only in gamete recognition but also in ensuring proper embryonic development."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "20"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nAdditional reports extend the discussion to related themes including the potential utility of zona pellucida proteins as targets for immunocontraception and cancer immunotherapy. However, across all the studies cited"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "21"}]}, {"type": "t", "text": ", there is no evidence linking or describing any function for OR2AP1. In summary, while the collected abstracts greatly enhance our understanding of zona pellucida glycoprotein function during oogenesis and fertilization, they do not provide any insights into the role or function of OR2AP1.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "G S Salzmann, J M Greve, R J Roller, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Biosynthesis of the sperm receptor during oogenesis in the mouse."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "EMBO J (1983)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/j.1460-2075.1983.tb01607.x"}], "href": "https://doi.org/10.1002/j.1460-2075.1983.tb01607.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11892795"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11892795"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Majid El-Mestrah, Philip E Castle, Girum Borossa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Subcellular distribution of ZP1, ZP2, and ZP3 glycoproteins during folliculogenesis and demonstration of their topographical disposition within the zona matrix of mouse ovarian oocytes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biol Reprod (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1095/biolreprod66.4.866"}], "href": "https://doi.org/10.1095/biolreprod66.4.866"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11906903"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11906903"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Ming Zhao, Lyn Gold, Ann M Ginsberg, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Conserved furin cleavage site not essential for secretion and integration of ZP3 into the extracellular egg coat of transgenic mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.22.9.3111-3120.2002"}], "href": "https://doi.org/10.1128/MCB.22.9.3111-3120.2002"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11940668"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11940668"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Zev Williams, Eveline S Litscher, Paul M Wassarman "}, {"type": "b", "children": [{"type": "t", "text": "Conversion of Ser to Thr residues at the sperm combining-site of mZP3 does not affect sperm receptor activity."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0006-291x(03)00044-5"}], "href": "https://doi.org/10.1016/s0006-291x(03"}, {"type": "t", "text": "00044-5) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12589785"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12589785"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Emily S Boja, Tanya Hoodbhoy, Henry M Fales, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Structural characterization of native mouse zona pellucida proteins using mass spectrometry."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M304026200"}], "href": "https://doi.org/10.1074/jbc.M304026200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12799386"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12799386"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Ming Zhao, Lyn Gold, Heidi Dorward, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutation of a conserved hydrophobic patch prevents incorporation of ZP3 into the zona pellucida surrounding mouse eggs."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.23.24.8982-8991.2003"}], "href": "https://doi.org/10.1128/MCB.23.24.8982-8991.2003"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14645511"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14645511"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Anne Dell, Sara Chalabi, Richard L Easton, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.2635507100"}], "href": "https://doi.org/10.1073/pnas.2635507100"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14673092"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14673092"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Luca Jovine, Huayu Qi, Zev Williams, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A duplicated motif controls assembly of zona pellucida domain proteins."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0401600101"}], "href": "https://doi.org/10.1073/pnas.0401600101"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15079052"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15079052"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Candace L Kerr, William F Hanna, Joel H Shaper, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Lewis X-containing glycans are specific and potent competitive inhibitors of the binding of ZP3 to complementary sites on capacitated, acrosome-intact mouse sperm."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biol Reprod (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1095/biolreprod.103.023812"}], "href": "https://doi.org/10.1095/biolreprod.103.023812"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15128590"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15128590"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Ming Zhao, Emily S Boja, Tanya Hoodbhoy, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochemistry (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1021/bi048958k"}], "href": "https://doi.org/10.1021/bi048958k"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15379548"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15379548"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Zev Williams, Eveline S Litscher, Luca Jovine, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Polypeptide encoded by mouse ZP3 exon-7 is necessary and sufficient for binding of mouse sperm in vitro."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Physiol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcp.20532"}], "href": "https://doi.org/10.1002/jcp.20532"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16245311"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16245311"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Megan L Lloyd, Sonia Nikolovski, Malcolm A Lawson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Innate antiviral resistance influences the efficacy of a recombinant murine cytomegalovirus immunocontraceptive vaccine."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Vaccine (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.vaccine.2006.08.019"}], "href": "https://doi.org/10.1016/j.vaccine.2006.08.019"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17007971"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17007971"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Tanya Hoodbhoy, Manuel Avilés, Boris Baibakov, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ZP2 and ZP3 traffic independently within oocytes prior to assembly into the extracellular zona pellucida."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00904-06"}], "href": "https://doi.org/10.1128/MCB.00904-06"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17047254"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17047254"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Melissa K Jungnickel, Keith A Sutton, Yanli Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Phosphoinositide-dependent pathways in mouse sperm are regulated by egg ZP3 and drive the acrosome reaction."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dev Biol (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ydbio.2006.12.023"}], "href": "https://doi.org/10.1016/j.ydbio.2006.12.023"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17258189"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17258189"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Ding Li, Shaofeng Cao, Chen Xu "}, {"type": "b", "children": [{"type": "t", "text": "Polypeptide backbone derived from carboxyl terminal of mouse ZP3 inhibits sperm-zona binding."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Reprod Dev (2007)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/mrd.20705"}], "href": "https://doi.org/10.1002/mrd.20705"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17290430"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17290430"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Magnus Monné, Ling Han, Thomas Schwend, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature07599"}], "href": "https://doi.org/10.1038/nature07599"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19052627"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19052627"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Maria Jimenez-Movilla, Jurrien Dean "}, {"type": "b", "children": [{"type": "t", "text": "ZP2 and ZP3 cytoplasmic tails prevent premature interactions and ensure incorporation into the zona pellucida."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.079988"}], "href": "https://doi.org/10.1242/jcs.079988"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21378311"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21378311"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Hongbin Xu, Fang Liu, Nopparat Srakaew, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Sperm arylsulfatase A binds to mZP2 and mZP3 glycoproteins in a nonenzymatic manner."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Reproduction (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1530/REP-11-0338"}], "href": "https://doi.org/10.1530/REP-11-0338"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22685254"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22685254"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Paul M Wassarman, Eveline S Litscher "}, {"type": "b", "children": [{"type": "t", "text": "Influence of the zona pellucida of the mouse egg on folliculogenesis and fertility."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Dev Biol (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1387/ijdb.120136pw"}], "href": "https://doi.org/10.1387/ijdb.120136pw"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23417405"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23417405"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Lei-Lei Gao, Chun-Xiang Zhou, Xiao-Lan Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "ZP3 is Required for Germinal Vesicle Breakdown in Mouse Oocyte Meiosis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/srep41272"}], "href": "https://doi.org/10.1038/srep41272"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28145526"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28145526"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Kamila Pulawska, Donata Ponikwicka-Tyszko, Weronika Lebiedzinska, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Novel expression of zona pellucida 3 protein in normal testis; potential functional implications."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Endocrinol (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.mce.2021.111502"}], "href": "https://doi.org/10.1016/j.mce.2021.111502"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34736966"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34736966"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Zhaokang Cui, Yajuan Lu, Yilong Miao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Transglutaminase 2 crosslinks zona pellucida glycoprotein 3 to prevent polyspermy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Death Differ (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41418-022-00933-0"}], "href": "https://doi.org/10.1038/s41418-022-00933-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "35017645"}], "href": "https://pubmed.ncbi.nlm.nih.gov/35017645"}]}]}]}
Synonyms OR2AP1P
Proteins O2AP1_HUMAN
NCBI Gene ID 121129
API
Download Associations
Predicted Functions View OR2AP1's ARCHS4 Predicted Functions.
Co-expressed Genes View OR2AP1's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View OR2AP1's ARCHS4 Predicted Functions.

Functional Associations

OR2AP1 has 651 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 41 datasets.

Click the + buttons to view associations for OR2AP1 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of OR2AP1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of OR2AP1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
ChEA Transcription Factor Targets 2022 transcription factors binding the promoter of OR2AP1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
CM4AI KOLF21J CRISPRi Gene Perturbation Atlas gene perturbations changing expression of OR2AP1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores cellular components containing OR2AP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
COMPARTMENTS Curated Protein Localization Evidence Scores 2025 cellular components containing OR2AP1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 cellular components co-occuring with OR2AP1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
COSMIC Cell Line Gene Mutation Profiles cell lines with OR2AP1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
DepMap CRISPR Gene Dependency cell lines with fitness changed by OR2AP1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
DISEASES Experimental Gene-Disease Association Evidence Scores 2025 diseases associated with OR2AP1 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 diseases co-occuring with OR2AP1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
ENCODE Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR2AP1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
ENCODE Transcription Factor Targets transcription factors binding the promoter of OR2AP1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
ESCAPE Omics Signatures of Genes and Proteins for Stem Cells PubMedIDs of publications reporting gene signatures containing OR2AP1 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
GeneSigDB Published Gene Signatures PubMedIDs of publications reporting gene signatures containing OR2AP1 from the GeneSigDB Published Gene Signatures dataset.
GEO Signatures of Differentially Expressed Genes for Diseases disease perturbations changing expression of OR2AP1 gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.
GEO Signatures of Differentially Expressed Genes for Gene Perturbations gene perturbations changing expression of OR2AP1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Kinase Perturbations kinase perturbations changing expression of OR2AP1 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of OR2AP1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GEO Signatures of Differentially Expressed Genes for Viral Infections virus perturbations changing expression of OR2AP1 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
GO Biological Process Annotations 2015 biological processes involving OR2AP1 gene from the curated GO Biological Process Annotations 2015 dataset.
GO Cellular Component Annotations 2015 cellular components containing OR2AP1 protein from the curated GO Cellular Component Annotations 2015 dataset.
GO Molecular Function Annotations 2015 molecular functions performed by OR2AP1 gene from the curated GO Molecular Function Annotations 2015 dataset.
GO Molecular Function Annotations 2023 molecular functions performed by OR2AP1 gene from the curated GO Molecular Function Annotations 2023 dataset.
GO Molecular Function Annotations 2025 molecular functions performed by OR2AP1 gene from the curated GO Molecular Function Annotations 2025 dataset.
GWAS Catalog SNP-Phenotype Associations 2025 phenotypes associated with OR2AP1 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles cell lines with high or low expression of OR2AP1 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
InterPro Predicted Protein Domain Annotations protein domains predicted for OR2AP1 protein from the InterPro Predicted Protein Domain Annotations dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of OR2AP1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
JASPAR Predicted Mouse Transcription Factor Targets 2025 transcription factors regulating expression of OR2AP1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
JASPAR Predicted Transcription Factor Targets transcription factors regulating expression of OR2AP1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
KEGG Pathways 2026 pathways involving OR2AP1 protein from the KEGG Pathways 2026 dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of OR2AP1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
LOCATE Predicted Protein Localization Annotations cellular components predicted to contain OR2AP1 protein from the LOCATE Predicted Protein Localization Annotations dataset.
MotifMap Predicted Transcription Factor Targets transcription factors regulating expression of OR2AP1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
Reactome Pathways 2014 pathways involving OR2AP1 protein from the Reactome Pathways dataset.
Reactome Pathways 2024 pathways involving OR2AP1 protein from the Reactome Pathways 2024 dataset.
Rummagene Transcription Factor Associations 2026 transcription factors regulating expression of OR2AP1 gene from the Rummagene Transcription Factor Associations 2026 dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of OR2AP1 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of OR2AP1 gene from the RummaGEO Gene Perturbation Signatures dataset.
TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 tissues co-occuring with OR2AP1 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.