OR2B8 Gene

Name olfactory receptor family 2 subfamily B member 8 (gene/pseudogene)
Description Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
NCBI Gene ID 65944
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Predicted Functions View OR2B8's ARCHS4 Predicted Functions.
Co-expressed Genes View OR2B8's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View OR2B8's ARCHS4 Predicted Functions.

Functional Associations

OR2B8 has 124 functional associations with biological entities spanning 5 categories (functional term, phrase or reference, disease, phenotype or trait, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 10 datasets.

Click the + buttons to view associations for OR2B8 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles tissue samples with high or low expression of OR2B8 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
CM4AI KOLF21J CRISPRi Gene Perturbation Atlas gene perturbations changing expression of OR2B8 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
GO Biological Process Annotations 2025 biological processes involving OR2B8 gene from the curated GO Biological Process Annotations2025 dataset.
GO Molecular Function Annotations 2025 molecular functions performed by OR2B8 gene from the curated GO Molecular Function Annotations 2025 dataset.
GWAS Catalog SNP-Phenotype Associations 2025 phenotypes associated with OR2B8 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of OR2B8 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
KEGG Pathways 2026 pathways involving OR2B8 protein from the KEGG Pathways 2026 dataset.
Rummagene Transcription Factor Associations 2026 transcription factors regulating expression of OR2B8 gene from the Rummagene Transcription Factor Associations 2026 dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of OR2B8 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of OR2B8 gene from the RummaGEO Gene Perturbation Signatures dataset.