OR2T10 Gene

HGNC Family	G protein-coupled receptors
Name	olfactory receptor, family 2, subfamily T, member 10
Description	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Synonyms	OR1-64
Proteins	O2T10_HUMAN
NCBI Gene ID	127069
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

OR2T10 has 807 functional associations with biological entities spanning 8 categories (molecular profile, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA, sequence feature) extracted from 46 datasets.

Click the + buttons to view associations for OR2T10 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

OR2T10 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of OR2T10 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of OR2T10 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of OR2T10 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR2T10 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of OR2T10 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of OR2T10 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing OR2T10 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with OR2T10 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of OR2T10 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with OR2T10 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by OR2T10 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with OR2T10 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at OR2T10 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR2T10 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of OR2T10 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing OR2T10 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of OR2T10 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of OR2T10 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GO Biological Process Annotations 2015	biological processes involving OR2T10 gene from the curated GO Biological Process Annotations 2015 dataset.
	GO Biological Process Annotations 2023	biological processes involving OR2T10 gene from the curated GO Biological Process Annotations 2023 dataset.
	GO Biological Process Annotations 2025	biological processes involving OR2T10 gene from the curated GO Biological Process Annotations2025 dataset.
	GO Cellular Component Annotations 2015	cellular components containing OR2T10 protein from the curated GO Cellular Component Annotations 2015 dataset.
	GO Molecular Function Annotations 2015	molecular functions performed by OR2T10 gene from the curated GO Molecular Function Annotations 2015 dataset.
	GO Molecular Function Annotations 2023	molecular functions performed by OR2T10 gene from the curated GO Molecular Function Annotations 2023 dataset.
	GO Molecular Function Annotations 2025	molecular functions performed by OR2T10 gene from the curated GO Molecular Function Annotations 2025 dataset.
	GTEx eQTL 2025	SNPs regulating expression of OR2T10 gene from the GTEx eQTL 2025 dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of OR2T10 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	GTEx Tissue Gene Expression Profiles 2023	tissues with high or low expression of OR2T10 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset.
	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	cell lines with high or low expression of OR2T10 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
	HPA Tissue Protein Expression Profiles	tissues with high or low expression of OR2T10 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for OR2T10 protein from the InterPro Predicted Protein Domain Annotations dataset.
	JASPAR Predicted Human Transcription Factor Targets 2025	transcription factors regulating expression of OR2T10 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
	JASPAR Predicted Transcription Factor Targets	transcription factors regulating expression of OR2T10 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.
	KEGG Pathways 2026	pathways involving OR2T10 protein from the KEGG Pathways 2026 dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of OR2T10 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	LOCATE Predicted Protein Localization Annotations	cellular components predicted to contain OR2T10 protein from the LOCATE Predicted Protein Localization Annotations dataset.
	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of OR2T10 gene from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	Reactome Pathways 2014	pathways involving OR2T10 protein from the Reactome Pathways dataset.
	Reactome Pathways 2024	pathways involving OR2T10 protein from the Reactome Pathways 2024 dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at OR2T10 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
	RummaGEO Drug Perturbation Signatures	drug perturbations changing expression of OR2T10 gene from the RummaGEO Drug Perturbation Signatures dataset.
	RummaGEO Gene Perturbation Signatures	gene perturbations changing expression of OR2T10 gene from the RummaGEO Gene Perturbation Signatures dataset.
	TCGA Signatures of Differentially Expressed Genes for Tumors	tissue samples with high or low expression of OR2T10 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.
	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	tissues with high expression of OR2T10 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores	tissues co-occuring with OR2T10 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.
	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	tissues co-occuring with OR2T10 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.