| HGNC Family | G protein-coupled receptors |
| Name | olfactory receptor, family 5, subfamily AS, member 1 |
| Description | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nAlthough none of the provided abstracts directly mention OR5AS1, they collectively highlight the pivotal roles of muscle‐specific chromatin regulators—most notably SMYD1 (also known as BOP)—in governing cardiac and skeletal muscle biology. In these studies, SMYD1 is characterized as a lysine methyltransferase with dual functions in transcriptional regulation and chromatin remodeling. It acts both as a transcriptional repressor and activator via histone modifications (e.g., H3K4 methylation) and operates downstream of major transcription factors such as MEF2C, thereby establishing a regulatory cascade that is essential for cardiomyocyte differentiation, ventricular chamber formation, and proper myofibrillogenesis in skeletal muscle."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond embryonic muscle development, additional studies detail how SMYD1 modulates adult cardiac energetics and stress responses. SMYD1 influences mitochondrial efficiency by regulating key metabolic controllers—such as PGC-1α and ERRα—and is crucial in maintaining proper cardiomyocyte proliferation under stress. Loss or downregulation of SMYD1 (or interference with its associated partners like skNAC and transcriptional corepressors) has been linked not only to impaired sarcomere organization and diminished myofibril assembly but also to altered endoplasmic reticulum and oxidative stress responses that precipitate hypertrophy and heart failure."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "10"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nAdditional reports expand on SMYD1’s multifaceted role by demonstrating its involvement in postnatal muscle maintenance, sarcomere formation, and even systemic metabolic regulation in tissues such as adipose. Structural insights reveal regulatory mechanisms such as autoinhibition, while interaction studies with proteins including skNAC and CtBP emphasize its role as an integrative hub coordinating histone methylation and acetylation events. Moreover, modulation of SMYD1 levels—whether through overexpression, knockdown, or post-translational modifications (e.g., sumoylation and redox regulation)—has significant consequences for cardiac adaptability, protection against ischemic injury, and the regulation of mitochondrial morphology via factors like OPA1. Collectively, these findings underscore the importance of muscle‐selective histone modifying enzymes in both developmental and mature cardiac muscle contexts."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "11", "end_ref": "22"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Paul D Gottlieb, Stephanie A Pierce, Robert J Sims, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng866"}], "href": "https://doi.org/10.1038/ng866"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11923873"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11923873"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Xungang Tan, Josep Rotllant, Huiqing Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SmyD1, a histone methyltransferase, is required for myofibril organization and muscle contraction in zebrafish embryos."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0509503103"}], "href": "https://doi.org/10.1073/pnas.0509503103"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16477022"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16477022"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Dillon Phan, Tara L Rasmussen, Osamu Nakagawa, et al. "}, {"type": "b", "children": [{"type": "t", "text": "BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Development (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/dev.01849"}], "href": "https://doi.org/10.1242/dev.01849"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15890826"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15890826"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Robert J Sims, Elizabeth K Weihe, Li Zhu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "m-Bop, a repressor protein essential for cardiogenesis, interacts with skNAC, a heart- and muscle-specific transcription factor."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M204121200"}], "href": "https://doi.org/10.1074/jbc.M204121200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12011100"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12011100"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Junco S Warren, Christopher M Tracy, Mickey R Miller, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1800680115"}], "href": "https://doi.org/10.1073/pnas.1800680115"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30061404"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30061404"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Chong Yon Park, Stephanie A Pierce, Morgan von Drehle, et al. "}, {"type": "b", "children": [{"type": "t", "text": "skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1013493107"}], "href": "https://doi.org/10.1073/pnas.1013493107"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21071677"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21071677"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Nualpun Sirinupong, Joseph Brunzelle, Jun Ye, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Crystal structure of cardiac-specific histone methyltransferase SmyD1 reveals unusual active site architecture."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M110.168187"}], "href": "https://doi.org/10.1074/jbc.M110.168187"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20943667"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20943667"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Sarah Franklin, Todd Kimball, Tara L Rasmussen, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The chromatin-binding protein Smyd1 restricts adult mammalian heart growth."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Physiol Heart Circ Physiol (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1152/ajpheart.00235.2016"}], "href": "https://doi.org/10.1152/ajpheart.00235.2016"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27663768"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27663768"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Tara L Rasmussen, Yanlin Ma, Chong Yon Park, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0121765"}], "href": "https://doi.org/10.1371/journal.pone.0121765"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25803368"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25803368"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Jun Yang, Allen D Everett "}, {"type": "b", "children": [{"type": "t", "text": "Hepatoma-derived growth factor represses SET and MYND domain containing 1 gene expression through interaction with C-terminal binding protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Mol Biol (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jmb.2008.12.080"}], "href": "https://doi.org/10.1016/j.jmb.2008.12.080"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19162039"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19162039"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "M David Stewart, Suhujey Lopez, Harika Nagandla, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dis Model Mech (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/dmm.022491"}], "href": "https://doi.org/10.1242/dmm.022491"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26935107"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26935107"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Harika Nagandla, Suhujey Lopez, Wei Yu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dev Biol (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ydbio.2015.12.005"}], "href": "https://doi.org/10.1016/j.ydbio.2015.12.005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26688546"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26688546"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Janine Berkholz, Laura Michalick, Barbara Munz "}, {"type": "b", "children": [{"type": "t", "text": "The E3 SUMO ligase Nse2 regulates sumoylation and nuclear-to-cytoplasmic translocation of skNAC-Smyd1 in myogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Sci (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1242/jcs.150334"}], "href": "https://doi.org/10.1242/jcs.150334"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25002400"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25002400"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Shin-Ichi Oka, Amira D Sabry, Amanda K Horiuchi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "PLoS One (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1371/journal.pone.0234913"}], "href": "https://doi.org/10.1371/journal.pone.0234913"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32574189"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32574189"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Janine Berkholz, Mickael Orgeur, Sigmar Stricker, et al. "}, {"type": "b", "children": [{"type": "t", "text": "skNAC and Smyd1 in transcriptional control."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2015.06.019"}], "href": "https://doi.org/10.1016/j.yexcr.2015.06.019"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26162853"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26162853"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Tong Liu, Changgong Wu, Mohit Raja Jain, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Master redox regulator Trx1 upregulates SMYD1 & modulates lysine methylation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbapap.2015.09.006"}], "href": "https://doi.org/10.1016/j.bbapap.2015.09.006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26410624"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26410624"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "D Srivastava, P D Gottlieb, E N Olson "}, {"type": "b", "children": [{"type": "t", "text": "Molecular mechanisms of ventricular hypoplasia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cold Spring Harb Symp Quant Biol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/sqb.2002.67.121"}], "href": "https://doi.org/10.1101/sqb.2002.67.121"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12858532"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12858532"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Marta W Szulik, Steven Valdez, Maureen Walsh, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Basic Res Cardiol (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00395-023-00991-6"}], "href": "https://doi.org/10.1007/s00395-023-00991-6"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37212935"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37212935"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Janine Berkholz, Regina Eberle, Klaus Boller, et al. "}, {"type": "b", "children": [{"type": "t", "text": "siRNA-mediated inhibition of skNAC and Smyd1 expression disrupts myofibril organization: Immunofluorescence and electron microscopy study in C2C12 cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Micron (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.micron.2018.02.009"}], "href": "https://doi.org/10.1016/j.micron.2018.02.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29499397"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29499397"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "Sandhya Singh, Aakash Gaur, Rakesh Kumar Sharma, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Musashi-2 causes cardiac hypertrophy and heart failure by inducing mitochondrial dysfunction through destabilizing Cluh and Smyd1 mRNA."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Basic Res Cardiol (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s00395-023-01016-y"}], "href": "https://doi.org/10.1007/s00395-023-01016-y"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37923788"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37923788"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Annunziata G Cicatiello, Annarita Nappi, Fabiana Franchini, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The histone methyltransferase SMYD1 is induced by thermogenic stimuli in adipose tissue."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Epigenomics (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.2217/epi-2023-0381"}], "href": "https://doi.org/10.2217/epi-2023-0381"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38440863"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38440863"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Jie Tang, Chenyang Wu, Yuxiang Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Resistance training up-regulates Smyd1 expression and inhibits oxidative stress and endoplasmic reticulum stress in the heart of middle-aged mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Free Radic Biol Med (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.freeradbiomed.2023.11.029"}], "href": "https://doi.org/10.1016/j.freeradbiomed.2023.11.029"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38042222"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38042222"}]}]}]}
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| Synonyms | OR11-168 |
| Proteins | O5AS1_HUMAN |
| NCBI Gene ID | 219447 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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OR5AS1 has 849 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 47 datasets.
Click the + buttons to view associations for OR5AS1 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of OR5AS1 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of OR5AS1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of OR5AS1 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
| BioGPS Mouse Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of OR5AS1 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR5AS1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR5AS1 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of OR5AS1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of OR5AS1 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| CM4AI KOLF21J CRISPRi Gene Perturbation Atlas | gene perturbations changing expression of OR5AS1 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing OR5AS1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores 2025 | cellular components containing OR5AS1 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with OR5AS1 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR5AS1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene Mutation Profiles | cell lines with OR5AS1 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by OR5AS1 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with OR5AS1 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at OR5AS1 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR5AS1 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of OR5AS1 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| GAD Gene-Disease Associations | diseases associated with OR5AS1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of OR5AS1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of OR5AS1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of OR5AS1 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GO Biological Process Annotations 2015 | biological processes involving OR5AS1 gene from the curated GO Biological Process Annotations 2015 dataset. | |
| GO Cellular Component Annotations 2015 | cellular components containing OR5AS1 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2015 | molecular functions performed by OR5AS1 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by OR5AS1 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GO Molecular Function Annotations 2025 | molecular functions performed by OR5AS1 gene from the curated GO Molecular Function Annotations 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of OR5AS1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles | cell lines with high or low expression of OR5AS1 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset. | |
| InterPro Predicted Protein Domain Annotations | protein domains predicted for OR5AS1 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of OR5AS1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Mouse Transcription Factor Targets 2025 | transcription factors regulating expression of OR5AS1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of OR5AS1 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| KEGG Pathways 2026 | pathways involving OR5AS1 protein from the KEGG Pathways 2026 dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR5AS1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain OR5AS1 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of OR5AS1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| Reactome Pathways 2014 | pathways involving OR5AS1 protein from the Reactome Pathways dataset. | |
| Reactome Pathways 2024 | pathways involving OR5AS1 protein from the Reactome Pathways 2024 dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at OR5AS1 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of OR5AS1 gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of OR5AS1 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of OR5AS1 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| Tabula Sapiens Gene-Cell Associations | cell types with high or low expression of OR5AS1 gene relative to other cell types from the Tabula Sapiens Gene-Cell Associations dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of OR5AS1 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with OR5AS1 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |
