| HGNC Family | G protein-coupled receptors |
| Name | olfactory receptor, family 8, subfamily B, member 4 (gene/pseudogene) |
| Description | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nAlthough none of these studies describe OR8B4, the provided abstracts collectively focus on the multifaceted role of the albumin D‐site‐binding protein (DBP) as a pivotal clock‐controlled transcription factor. DBP is rhythmically activated by the core circadian regulators BMAL1 and CLOCK, whose binding to E‐box elements drives cyclic chromatin remodeling and robust transcription of DBP in multiple tissues. This transcriptional cycling underlies the generation of high‐amplitude circadian outputs that influence the temporal regulation of key physiologic processes, including gene expression in the liver, kidney and brain."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "7"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its core function in circadian timing, DBP orchestrates the rhythmic transcription of a number of downstream genes involved in metabolic homeostasis, detoxification, electrolyte balance, and even neuronal excitability. The studies demonstrate that DBP, along with its paralogous PAR bZip transcription factors (TEF and HLF), regulates the expression of enzymes critical for drug metabolism and vitamin B6 homeostasis, and plays a role in maintaining cardiovascular function and normal pancreatic islet gene expression. Loss or altered regulation of DBP is associated with pronounced phenotypes such as heightened sensitivity to xenobiotics, epilepsies, and metabolic dysregulation."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "8", "end_ref": "13"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nAt the mechanistic level, DBP expression and function are finely tuned by several intracellular signaling pathways and chromatin modifications. Key regulatory inputs include PI3K signaling, histone deacetylation, and dynamic protein–protein interactions with factors such as CRY1, KLF9/KLF13, and the D-box repressor E4BP4. These regulatory mechanisms not only adjust DBP’s transcriptional burst frequency and amplitude but also integrate external cues—such as photoperiod, temperature oscillations, and inflammatory signals—into the circadian system, thereby ensuring that downstream gene expression adapts appropriately to environmental and metabolic conditions."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "14", "end_ref": "19"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Steven A Brown, Gottlieb Zumbrunn, Fabienne Fleury-Olela, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Rhythms of mammalian body temperature can sustain peripheral circadian clocks."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Curr Biol (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/s0960-9822(02)01145-4"}], "href": "https://doi.org/10.1016/s0960-9822(02"}, {"type": "t", "text": "01145-4) PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12372249"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12372249"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Frédéric Gachon, Philippe Fonjallaz, Francesca Damiola, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The loss of circadian PAR bZip transcription factors results in epilepsy."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Dev (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/gad.301404"}], "href": "https://doi.org/10.1101/gad.301404"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15175240"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15175240"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Jürgen A Ripperger, Ueli Schibler "}, {"type": "b", "children": [{"type": "t", "text": "Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng1738"}], "href": "https://doi.org/10.1038/ng1738"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16474407"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16474407"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Frédéric Gachon, Fabienne Fleury Olela, Olivier Schaad, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Metab (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cmet.2006.04.015"}], "href": "https://doi.org/10.1016/j.cmet.2006.04.015"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16814730"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16814730"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Saskia Petrzilka, Cornelia Taraborrelli, Gionata Cavadini, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Clock gene modulation by TNF-alpha depends on calcium and p38 MAP kinase signaling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Rhythms (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1177/0748730409336579"}], "href": "https://doi.org/10.1177/0748730409336579"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19625730"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19625730"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Annie Mercier Zuber, Gabriel Centeno, Sylvain Pradervand, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Molecular clock is involved in predictive circadian adjustment of renal function."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0904890106"}], "href": "https://doi.org/10.1073/pnas.0904890106"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19805330"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19805330"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Markus Stratmann, Frédéric Stadler, Filippo Tamanini, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Flexible phase adjustment of circadian albumin D site-binding protein (DBP) gene expression by CRYPTOCHROME1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes Dev (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1101/gad.578810"}], "href": "https://doi.org/10.1101/gad.578810"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20551177"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20551177"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Qing Wang, Marc Maillard, Ueli Schibler, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Am J Physiol Regul Integr Comp Physiol (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1152/ajpregu.00241.2010"}], "href": "https://doi.org/10.1152/ajpregu.00241.2010"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20686175"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20686175"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Hitoshi Ando, Masafumi Kumazaki, Yuya Motosugi, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Circadian Dbp transcription relies on highly dynamic BMAL1-CLOCK interaction with E boxes and requires the proteasome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2012.08.012"}], "href": "https://doi.org/10.1016/j.molcel.2012.08.012"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22981862"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22981862"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Thomas Curie, Valérie Mongrain, Stéphane Dorsaz, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Homeostatic and circadian contribution to EEG and molecular state variables of sleep regulation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sleep (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.5665/sleep.2440"}], "href": "https://doi.org/10.5665/sleep.2440"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23450268"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23450268"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Hiroko Nakabayashi, Yasuharu Ohta, Masayoshi Yamamoto, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1β gene expression in pancreatic islet β-cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2013.03.084"}], "href": "https://doi.org/10.1016/j.bbrc.2013.03.084"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23567972"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23567972"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Kengo Hamamura, Naoya Matsunaga, Eriko Ikeda, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Induction of "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "Dbp"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " by a histone deacetylase inhibitor is involved in amelioration of insulin sensitivity via adipocyte differentiation in ob/ob mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Chronobiol Int (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/07420528.2019.1602841"}], "href": "https://doi.org/10.1080/07420528.2019.1602841"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31070057"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31070057"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Paul Kwangho Kwon, Hyo-Min Kim, Sung Wook Kim, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Poly(C) Motif in the Proximal Promoter Region of the D Site-Binding Protein Gene ("}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "Dbp"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": ") Drives Its High-Amplitude Oscillation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.00101-19"}], "href": "https://doi.org/10.1128/MCB.00101-19"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31160492"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31160492"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Hikari Yoshitane, Yoshimasa Asano, Aya Sagami, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Functional D-box sequences reset the circadian clock and drive mRNA rhythms."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Commun Biol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s42003-019-0522-3"}], "href": "https://doi.org/10.1038/s42003-019-0522-3"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31428688"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31428688"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Joseph R Knoedler, José Ávila-Mendoza, Arasakumar Subramani, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Commun (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41467-022-33733-8"}], "href": "https://doi.org/10.1038/s41467-022-33733-8"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36241625"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36241625"}]}]}]}
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| Synonyms | OR8B4P, OR11-315 |
| Proteins | OR8B4_HUMAN |
| NCBI Gene ID | 283162 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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OR8B4 has 744 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 56 datasets.
Click the + buttons to view associations for OR8B4 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of OR8B4 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of OR8B4 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of OR8B4 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
| BioGPS Mouse Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of OR8B4 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR8B4 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR8B4 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of OR8B4 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of OR8B4 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing OR8B4 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores 2025 | cellular components containing OR8B4 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with OR8B4 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR8B4 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene Mutation Profiles | cell lines with OR8B4 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
| dbGAP Gene-Trait Associations | traits associated with OR8B4 gene in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by OR8B4 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with OR8B4 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at OR8B4 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR8B4 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of OR8B4 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| ESCAPE Omics Signatures of Genes and Proteins for Stem Cells | PubMedIDs of publications reporting gene signatures containing OR8B4 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset. | |
| GeneSigDB Published Gene Signatures | PubMedIDs of publications reporting gene signatures containing OR8B4 from the GeneSigDB Published Gene Signatures dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of OR8B4 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of OR8B4 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Small Molecules | small molecule perturbations changing expression of OR8B4 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of OR8B4 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GO Biological Process Annotations 2015 | biological processes involving OR8B4 gene from the curated GO Biological Process Annotations 2015 dataset. | |
| GO Biological Process Annotations 2023 | biological processes involving OR8B4 gene from the curated GO Biological Process Annotations 2023 dataset. | |
| GO Biological Process Annotations 2025 | biological processes involving OR8B4 gene from the curated GO Biological Process Annotations2025 dataset. | |
| GO Cellular Component Annotations 2015 | cellular components containing OR8B4 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2015 | molecular functions performed by OR8B4 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by OR8B4 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GO Molecular Function Annotations 2025 | molecular functions performed by OR8B4 gene from the curated GO Molecular Function Annotations 2025 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of OR8B4 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GWAS Catalog SNP-Phenotype Associations 2025 | phenotypes associated with OR8B4 gene in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. | |
| Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles | cell lines with high or low expression of OR8B4 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset. | |
| HPA Tissue Protein Expression Profiles | tissues with high or low expression of OR8B4 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset. | |
| InterPro Predicted Protein Domain Annotations | protein domains predicted for OR8B4 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of OR8B4 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Mouse Transcription Factor Targets 2025 | transcription factors regulating expression of OR8B4 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of OR8B4 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| KEGG Pathways 2026 | pathways involving OR8B4 protein from the KEGG Pathways 2026 dataset. | |
| Kinase Library Tyrosine Kinome Atlas | kinases that phosphorylate OR8B4 protein from the Kinase Library Tyrosine Kinome Atlas dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR8B4 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of OR8B4 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain OR8B4 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of OR8B4 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| Reactome Pathways 2014 | pathways involving OR8B4 protein from the Reactome Pathways dataset. | |
| Reactome Pathways 2024 | pathways involving OR8B4 protein from the Reactome Pathways 2024 dataset. | |
| Roadmap Epigenomics Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at OR8B4 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of OR8B4 gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| RummaGEO Drug Perturbation Signatures | drug perturbations changing expression of OR8B4 gene from the RummaGEO Drug Perturbation Signatures dataset. | |
| RummaGEO Gene Perturbation Signatures | gene perturbations changing expression of OR8B4 gene from the RummaGEO Gene Perturbation Signatures dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of OR8B4 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
| TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 | tissues with high expression of OR8B4 protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with OR8B4 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |
| WikiPathways Pathways 2014 | pathways involving OR8B4 protein from the Wikipathways Pathways 2014 dataset. | |
