| HGNC Family | G protein-coupled receptors |
| Name | olfactory receptor, family 8, subfamily K, member 5 |
| Description | Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008] |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe collection of abstracts provided is entirely focused on neural cell adhesion molecule L1 and its regulation by proteolytic processing, binding interactions, and downstream signaling pathways that govern key neural processes such as neurite outgrowth, axon guidance, synaptic plasticity, neuronal survival, and regeneration. Several studies describe how various proteases—including ADAM10, ADAM17, BACE1, neuropsin, and cathepsin E—target L1 to generate fragments that modulate cellular adhesion, migration, and neuritogenesis. In addition, the work highlights how L1 cooperates with other molecules (for example, integrins, Eph/ephrins, polysialylated NCAM, and GAP‑43) to fine‑tune neuronal network formation and repair following injury, as well as influencing tumor angiogenesis and immune cell trafficking."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "23"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIt is important to note, however, that none of the abstracts mention or provide any information regarding OR8K5. Consequently, while the literature here richly details multiple aspects of L1 biology and its impact on neuronal function and pathology, no functional insights about OR8K5 can be extracted from these sources. To understand the role of OR8K5, additional literature specifically addressing this gene would need to be examined."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "23"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Elena De Angelis, Alex Watkins, Michael Schäfer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Disease-associated mutations in L1 CAM interfere with ligand interactions and cell-surface expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Hum Mol Genet (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/hmg/11.1.1"}], "href": "https://doi.org/10.1093/hmg/11.1.1"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "11772994"}], "href": "https://pubmed.ncbi.nlm.nih.gov/11772994"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Rong-Yu Liu, Ralf-Steffen Schmid, William D Snider, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NGF enhances sensory axon growth induced by laminin but not by the L1 cell adhesion molecule."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Neurosci (2002)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1006/mcne.2002.1107"}], "href": "https://doi.org/10.1006/mcne.2002.1107"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12056835"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12056835"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Ina Kalus, Birthe Schnegelsberg, Nabil G Seidah, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M208351200"}], "href": "https://doi.org/10.1074/jbc.M208351200"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12529374"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12529374"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Marcel Dihné, Christian Bernreuther, Mirjam Sibbe, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A new role for the cell adhesion molecule L1 in neural precursor cell proliferation, differentiation, and transmitter-specific subtype generation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2003)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12878705"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12878705"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Kazumasa Matsumoto-Miyai, Ayako Ninomiya, Hironobu Yamasaki, et al. "}, {"type": "b", "children": [{"type": "t", "text": "NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2003)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12944500"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12944500"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Chanland Roonprapunt, Wencheng Huang, Ray Grill, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Soluble cell adhesion molecule L1-Fc promotes locomotor recovery in rats after spinal cord injury."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurotrauma (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/089771503322385809"}], "href": "https://doi.org/10.1089/089771503322385809"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14577865"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14577865"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Janice W S Law, Alan Y W Lee, Mu Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Decreased anxiety, altered place learning, and increased CA1 basal excitatory synaptic transmission in mice with conditional ablation of the neural cell adhesion molecule L1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2003)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14614101"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14614101"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "A E Wiencken-Barger, J Mavity-Hudson, U Bartsch, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The role of L1 in axon pathfinding and fasciculation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cereb Cortex (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/cercor/bhg110"}], "href": "https://doi.org/10.1093/cercor/bhg110"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "14704209"}], "href": "https://pubmed.ncbi.nlm.nih.gov/14704209"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Valérie Castellani, Julien Falk, Geneviève Rougon "}, {"type": "b", "children": [{"type": "t", "text": "Semaphorin3A-induced receptor endocytosis during axon guidance responses is mediated by L1 CAM."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Neurosci (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.mcn.2004.01.010"}], "href": "https://doi.org/10.1016/j.mcn.2004.01.010"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15121181"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15121181"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Armen K Saghatelyan, Alexander G Nikonenko, Mu Sun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Reduced GABAergic transmission and number of hippocampal perisomatic inhibitory synapses in juvenile mice deficient in the neural cell adhesion molecule L1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Neurosci (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.mcn.2004.01.008"}], "href": "https://doi.org/10.1016/j.mcn.2004.01.008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15121190"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15121190"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Ling Cheng, Kouichi Itoh, Vance Lemmon "}, {"type": "b", "children": [{"type": "t", "text": "L1-mediated branching is regulated by two ezrin-radixin-moesin (ERM)-binding sites, the RSLE region and a novel juxtamembrane ERM-binding region."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1523/JNEUROSCI.4097-04.2005"}], "href": "https://doi.org/10.1523/JNEUROSCI.4097-04.2005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15647482"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15647482"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Gabriele Loers, Suzhen Chen, Martin Grumet, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Signal transduction pathways implicated in neural recognition molecule L1 triggered neuroprotection and neuritogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurochem (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1471-4159.2004.02983.x"}], "href": "https://doi.org/10.1111/j.1471-4159.2004.02983.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15748164"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15748164"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Jian Chen, Christian Bernreuther, Marcel Dihné, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Cell adhesion molecule l1-transfected embryonic stem cells with enhanced survival support regrowth of corticospinal tract axons in mice after spinal cord injury."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurotrauma (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1089/neu.2005.22.896"}], "href": "https://doi.org/10.1089/neu.2005.22.896"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16083356"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16083356"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Yi Zhang, Xuenong Bo, Ralf Schoepfer, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.0505164102"}], "href": "https://doi.org/10.1073/pnas.0505164102"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16195382"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16195382"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Thorsten Maretzky, Marc Schulte, Andreas Ludwig, et al. "}, {"type": "b", "children": [{"type": "t", "text": "L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biol (2005)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1128/MCB.25.20.9040-9053.2005"}], "href": "https://doi.org/10.1128/MCB.25.20.9040-9053.2005"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16199880"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16199880"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Oleg Senkov, Mu Sun, Birgit Weinhold, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Polysialylated neural cell adhesion molecule is involved in induction of long-term potentiation and memory acquisition and consolidation in a fear-conditioning paradigm."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Neurosci (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1523/JNEUROSCI.0878-06.2006"}], "href": "https://doi.org/10.1523/JNEUROSCI.0878-06.2006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17050727"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17050727"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Luigi Maddaluno, Sue Ellen Verbrugge, Chiara Martinoli, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Exp Med (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1084/jem.20081211"}], "href": "https://doi.org/10.1084/jem.20081211"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19273627"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19273627"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Galina P Demyanenko, Priscila F Siesser, Amanda G Wright, et al. "}, {"type": "b", "children": [{"type": "t", "text": "L1 and CHL1 Cooperate in Thalamocortical Axon Targeting."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cereb Cortex (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/cercor/bhq115"}], "href": "https://doi.org/10.1093/cercor/bhq115"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "20576928"}], "href": "https://pubmed.ncbi.nlm.nih.gov/20576928"}]}, {"type": "r", "ref": 19, "children": [{"type": "t", "text": "Javier Gilabert-Juan, Esther Castillo-Gomez, Marta Pérez-Rando, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Chronic stress induces changes in the structure of interneurons and in the expression of molecules related to neuronal structural plasticity and inhibitory neurotransmission in the amygdala of adult mice."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Neurol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.expneurol.2011.07.009"}], "href": "https://doi.org/10.1016/j.expneurol.2011.07.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21819983"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21819983"}]}, {"type": "r", "ref": 20, "children": [{"type": "t", "text": "David Lutz, Gerrit Wolters-Eisfeld, Gunjan Joshi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Generation and nuclear translocation of sumoylated transmembrane fragment of cell adhesion molecule L1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M112.346759"}], "href": "https://doi.org/10.1074/jbc.M112.346759"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22431726"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22431726"}]}, {"type": "r", "ref": 21, "children": [{"type": "t", "text": "Lujia Zhou, Soraia Barão, Mathias Laga, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The neural cell adhesion molecules L1 and CHL1 are cleaved by BACE1 protease in vivo."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M112.377465"}], "href": "https://doi.org/10.1074/jbc.M112.377465"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22692213"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22692213"}]}, {"type": "r", "ref": 22, "children": [{"type": "t", "text": "Elena Magrini, Alessandra Villa, Francesca Angiolini, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Clin Invest (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1172/JCI70683"}], "href": "https://doi.org/10.1172/JCI70683"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25157817"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25157817"}]}, {"type": "r", "ref": 23, "children": [{"type": "t", "text": "Yilin Tai, Nicholas B Gallo, Minghui Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Neuron (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.neuron.2019.02.009"}], "href": "https://doi.org/10.1016/j.neuron.2019.02.009"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30846310"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30846310"}]}]}]}
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| Synonyms | OR11-174 |
| Proteins | OR8K5_HUMAN |
| NCBI Gene ID | 219453 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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OR8K5 has 832 functional associations with biological entities spanning 7 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 44 datasets.
Click the + buttons to view associations for OR8K5 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of OR8K5 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset. | |
| Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray | tissue samples with high or low expression of OR8K5 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset. | |
| Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles | tissues with high or low expression of OR8K5 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset. | |
| BioGPS Human Cell Type and Tissue Gene Expression Profiles | cell types and tissues with high or low expression of OR8K5 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset. | |
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR8K5 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| ChEA Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR8K5 gene from the CHEA Transcription Factor Binding Site Profiles dataset. | |
| ChEA Transcription Factor Targets | transcription factors binding the promoter of OR8K5 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset. | |
| ChEA Transcription Factor Targets 2022 | transcription factors binding the promoter of OR8K5 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores | cellular components containing OR8K5 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. | |
| COMPARTMENTS Curated Protein Localization Evidence Scores 2025 | cellular components containing OR8K5 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. | |
| COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 | cellular components co-occuring with OR8K5 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. | |
| COSMIC Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR8K5 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset. | |
| COSMIC Cell Line Gene Mutation Profiles | cell lines with OR8K5 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. | |
| DepMap CRISPR Gene Dependency | cell lines with fitness changed by OR8K5 gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset. | |
| DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 | diseases co-occuring with OR8K5 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. | |
| ENCODE Histone Modification Site Profiles | histone modification site profiles with high histone modification abundance at OR8K5 gene from the ENCODE Histone Modification Site Profiles dataset. | |
| ENCODE Transcription Factor Binding Site Profiles | transcription factor binding site profiles with transcription factor binding evidence at the promoter of OR8K5 gene from the ENCODE Transcription Factor Binding Site Profiles dataset. | |
| ENCODE Transcription Factor Targets | transcription factors binding the promoter of OR8K5 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset. | |
| GEO Signatures of Differentially Expressed Genes for Gene Perturbations | gene perturbations changing expression of OR8K5 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Kinase Perturbations | kinase perturbations changing expression of OR8K5 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset. | |
| GEO Signatures of Differentially Expressed Genes for Viral Infections | virus perturbations changing expression of OR8K5 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset. | |
| GO Biological Process Annotations 2015 | biological processes involving OR8K5 gene from the curated GO Biological Process Annotations 2015 dataset. | |
| GO Biological Process Annotations 2023 | biological processes involving OR8K5 gene from the curated GO Biological Process Annotations 2023 dataset. | |
| GO Cellular Component Annotations 2015 | cellular components containing OR8K5 protein from the curated GO Cellular Component Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2015 | molecular functions performed by OR8K5 gene from the curated GO Molecular Function Annotations 2015 dataset. | |
| GO Molecular Function Annotations 2023 | molecular functions performed by OR8K5 gene from the curated GO Molecular Function Annotations 2023 dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of OR8K5 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GTEx Tissue Gene Expression Profiles 2023 | tissues with high or low expression of OR8K5 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles 2023 dataset. | |
| Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles | cell lines with high or low expression of OR8K5 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset. | |
| InterPro Predicted Protein Domain Annotations | protein domains predicted for OR8K5 protein from the InterPro Predicted Protein Domain Annotations dataset. | |
| JASPAR Predicted Human Transcription Factor Targets 2025 | transcription factors regulating expression of OR8K5 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset. | |
| JASPAR Predicted Mouse Transcription Factor Targets 2025 | transcription factors regulating expression of OR8K5 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset. | |
| JASPAR Predicted Transcription Factor Targets | transcription factors regulating expression of OR8K5 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. | |
| KEGG Pathways 2026 | pathways involving OR8K5 protein from the KEGG Pathways 2026 dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of OR8K5 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |
| KnockTF Gene Expression Profiles with Transcription Factor Perturbations | transcription factor perturbations changing expression of OR8K5 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset. | |
| LOCATE Predicted Protein Localization Annotations | cellular components predicted to contain OR8K5 protein from the LOCATE Predicted Protein Localization Annotations dataset. | |
| MotifMap Predicted Transcription Factor Targets | transcription factors regulating expression of OR8K5 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. | |
| Pathway Commons Protein-Protein Interactions | interacting proteins for OR8K5 from the Pathway Commons Protein-Protein Interactions dataset. | |
| Reactome Pathways 2014 | pathways involving OR8K5 protein from the Reactome Pathways dataset. | |
| Reactome Pathways 2024 | pathways involving OR8K5 protein from the Reactome Pathways 2024 dataset. | |
| Rummagene Transcription Factor Associations 2026 | transcription factors regulating expression of OR8K5 gene from the Rummagene Transcription Factor Associations 2026 dataset. | |
| TCGA Signatures of Differentially Expressed Genes for Tumors | tissue samples with high or low expression of OR8K5 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset. | |
| TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 | tissues co-occuring with OR8K5 protein in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset. | |
