| HGNC Family | Cadherins |
| Name | protocadherin beta cluster |
| Description | The protocadherin beta cluster is one of three related gene clusters tandemly linked on chromosome five. The protocadherin genes have an immunoglobulin-like genomic organization, suggesting that a novel mechanism may be involved in their regulation and expression. The beta cluster contains 16 genes and 3 pseudogenes. Each gene product contains 6 extracellular cadherin domains and a cytoplasmic tail that diverges from other cadherin superfamily members. Unlike the alpha and gamma clusters, the beta cluster has a variable region but lacks a constant region. Without this downstream region of shared exons, each transcript encodes a unique cytoplasmic tail. The specific functions of these one-exon gene products are unknown; however, they are thought to play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008] |
| Synonyms | PCDH3 |
| NCBI Gene ID | 56116 |
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| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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PCDHB@ has 11 functional associations with biological entities spanning 1 categories (functional term, phrase or reference) extracted from 2 datasets.
Click the + buttons to view associations for PCDHB@ from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| GeneRIF Biological Term Annotations | biological terms co-occuring with PCDHB@ gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. | |
| PFOCR Pathway Figure Associations 2023 | pathways involving PCDHB@ protein from the PFOCR Pathway Figure Associations 2023 dataset. | |
