PSKH2 Gene

Name	protein serine kinase H2
Proteins	KPSH2_HUMAN
NCBI Gene ID	85481
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Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

PSKH2 has 944 functional associations with biological entities spanning 8 categories (molecular profile, organism, disease, phenotype or trait, functional term, phrase or reference, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 40 datasets.

Click the + buttons to view associations for PSKH2 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

PSKH2 Gene

Functional Associations

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Funding

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by PSKH2 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PSKH2 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of PSKH2 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of PSKH2 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of PSKH2 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of PSKH2 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Gene Mutation Profiles	cell lines with PSKH2 gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset.
	CHEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PSKH2 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	CHEA Transcription Factor Targets	transcription factors binding the promoter of PSKH2 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of PSKH2 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with PSKH2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	DISEASES Experimental Gene-Disease Assocation Evidence Scores	diseases associated with PSKH2 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.
	DisGeNET Gene-Disease Associations	diseases associated with PSKH2 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at PSKH2 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PSKH2 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of PSKH2 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	GAD High Level Gene-Disease Associations	diseases associated with PSKH2 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with PSKH2 gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing PSKH2 from the GeneSigDB Published Gene Signatures dataset.
	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	gene perturbations changing expression of PSKH2 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	kinase perturbations changing expression of PSKH2 gene from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of PSKH2 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	transcription factor perturbations changing expression of PSKH2 gene from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
	GEO Signatures of Differentially Expressed Genes for Viral Infections	virus perturbations changing expression of PSKH2 gene from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.
	GO Biological Process Annotations	biological processes involving PSKH2 gene from the curated GO Biological Process Annotations dataset.
	GO Molecular Function Annotations	molecular functions performed by PSKH2 gene from the curated GO Molecular Function Annotations dataset.
	GTEx Tissue Gene Expression Profiles	tissues with high or low expression of PSKH2 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	cell lines with high or low expression of PSKH2 gene relative to other cell lines from the Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles dataset.
	HMDB Metabolites of Enzymes	interacting metabolites for PSKH2 protein from the curated HMDB Metabolites of Enzymes dataset.
	HPA Tissue Protein Expression Profiles	tissues with high or low expression of PSKH2 protein relative to other tissues from the HPA Tissue Protein Expression Profiles dataset.
	HuGE Navigator Gene-Phenotype Associations	phenotypes associated with PSKH2 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
	InterPro Predicted Protein Domain Annotations	protein domains predicted for PSKH2 protein from the InterPro Predicted Protein Domain Annotations dataset.
	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	cell lines with high or low copy number of PSKH2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.
	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	transcription factor perturbations changing expression of PSKH2 gene from the KnockTF Gene Expression Profiles with Transcription Factor Perturbations dataset.
	LOCATE Predicted Protein Localization Annotations	cellular components predicted to contain PSKH2 protein from the LOCATE Predicted Protein Localization Annotations dataset.
	MotifMap Predicted Transcription Factor Targets	transcription factors regulating expression of PSKH2 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
	Pathway Commons Protein-Protein Interactions	interacting proteins for PSKH2 from the Pathway Commons Protein-Protein Interactions dataset.
	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	cell types and tissues with high or low DNA methylation of PSKH2 gene relative to other cell types and tissues from the Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles dataset.
	Roadmap Epigenomics Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at PSKH2 gene from the Roadmap Epigenomics Histone Modification Site Profiles dataset.
	TCGA Signatures of Differentially Expressed Genes for Tumors	tissue samples with high or low expression of PSKH2 gene relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.