PSMA7 Gene

HGNC Family	Proteasome (prosome, macropain) subunits (PSM)
Name	proteasome (prosome, macropain) subunit, alpha type, 7
Description	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9. [provided by RefSeq, Jul 2012]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nProteasome subunit alpha type‐7 (PSMA7) is a critical component of the 20S core proteasome complex that orchestrates intracellular protein degradation and maintains protein homeostasis. Its function is dynamically regulated by post‐translational modifications – for instance, tyrosine phosphorylation by c‐Abl/Arg kinases (which compromises proteasome‐dependent proteolysis and impacts cell cycle progression) and dephosphorylation events that affect its ubiquitination status and subsequent turnover. Moreover, structural studies have revealed that PSMA7 possesses distinct self‐assembly properties and interacts with other α‐subunits during the formation of proteasome assembly intermediates, ensuring the proper assembly of the mature proteasome."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "4"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its canonical role in proteolysis, PSMA7 has been implicated in modulating inflammatory and angiogenic processes. In patients with inflammatory bowel disease (IBD), markedly elevated levels of salivary exosomal PSMA7 correlate with enhanced proteasome activity and inflammatory responses, underscoring its potential as a non‐invasive biomarker for IBD. In addition, interactions between PSMA7 and regulatory proteins – such as calcineurin B and EMAP‐II – affect the degradation of hypoxia‐inducible factor‐1α (HIF‑1α) and subsequently modulate the expression of vascular endothelial growth factor (VEGF), which are key events in angiogenesis and may contribute to anticancer and antiviral effects."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "5", "end_ref": "7"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nAberrant expression of PSMA7 is closely associated with cancer development and progression, although its role appears to be context‐dependent. In colorectal cancer, increased PSMA7 expression correlates with liver metastasis, poor patient survival, and adverse clinicopathological parameters, while mechanistic studies indicate that PSMA7 may drive tumorigenicity by engaging with other proteins that promote invasion and metastasis. In high‐grade serous ovarian cancer, PSMA7 forms part of a regulatory axis with acylaminoacyl peptide hydrolase (APEH) that maintains proteasome activity under proteotoxic stress, thereby promoting cancer cell survival. Conversely, in lung adenocarcinoma, PSMA7 appears to inhibit tumor cell proliferation and invasion, suggesting a potential tumor‐suppressive role. Its role in gastric cancer and cutaneous squamous cell carcinoma further highlights a duality in function, as PSMA7 either fosters malignant progression or may serve as an exploitable biomarker for therapeutic intervention. A pan‐cancer analysis emphasizes that amplification of the PSMA7 gene in the 20q13.33 region is linked to adverse prognosis, likely through its influence over proteasome and protease‐related pathways."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "8", "end_ref": "17"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xuan Liu, Wei Huang, Chufang Li, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Interaction between c-Abl and Arg tyrosine kinases and proteasome subunit PSMA7 regulates proteasome degradation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell (2006)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.molcel.2006.04.007"}], "href": "https://doi.org/10.1016/j.molcel.2006.04.007"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "16678104"}], "href": "https://pubmed.ncbi.nlm.nih.gov/16678104"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Dapei Li, Qincai Dong, Qingping Tao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Rep (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.celrep.2014.12.044"}], "href": "https://doi.org/10.1016/j.celrep.2014.12.044"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25620702"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25620702"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Kentaro Ishii, Masanori Noda, Hirokazu Yagi, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Disassembly of the self-assembled, double-ring structure of proteasome α7 homo-tetradecamer by α6."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/srep18167"}], "href": "https://doi.org/10.1038/srep18167"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26657688"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26657688"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Géraud-Sébastien Apcher, Joanne Maitland, Simon Dawson, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The alpha4 and alpha7 subunits and assembly of the 20S proteasome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "FEBS Lett (2004)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.febslet.2004.05.067"}], "href": "https://doi.org/10.1016/j.febslet.2004.05.067"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15225636"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15225636"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Xiaowen Zheng, Feng Chen, Qian Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Salivary exosomal PSMA7: a promising biomarker of inflammatory bowel disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Protein Cell (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s13238-017-0413-7"}], "href": "https://doi.org/10.1007/s13238-017-0413-7"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28523434"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28523434"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Ning Li, Zhouzhou Zhang, Wen Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Calcineurin B subunit interacts with proteasome subunit alpha type 7 and represses hypoxia-inducible factor-1α activity via the proteasome pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2011.01.055"}], "href": "https://doi.org/10.1016/j.bbrc.2011.01.055"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21256111"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21256111"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Anita T Tandle, Maura Calvani, Badarch Uranchimeg, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Endothelial monocyte activating polypeptide-II modulates endothelial cell responses by degrading hypoxia-inducible factor-1alpha through interaction with PSMA7, a component of the proteasome."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Cell Res (2009)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.yexcr.2009.03.021"}], "href": "https://doi.org/10.1016/j.yexcr.2009.03.021"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19362550"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19362550"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Xiao-tong Hu, Wei Chen, Da Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The proteasome subunit PSMA7 located on the 20q13 amplicon is overexpressed and associated with liver metastasis in colorectal cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncol Rep (2008)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18202793"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18202793"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Liuzhong Yang, Zheng Tang, Huiqiang Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PSMA7 directly interacts with NOD1 and regulates its function."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Physiol Biochem (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1159/000350113"}], "href": "https://doi.org/10.1159/000350113"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23839082"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23839082"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Apoorva Tangri, Kinzie Lighty, Jagadish Loganathan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Deubiquitinase UCHL1 Maintains Protein Homeostasis through the PSMA7-APEH-Proteasome Axis in High-grade Serous Ovarian Carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cancer Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1158/1541-7786.MCR-20-0883"}], "href": "https://doi.org/10.1158/1541-7786.MCR-20-0883"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33753553"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33753553"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "Jia-Yu Tan, Xiang Huang, Ya-Ling Luo "}, {"type": "b", "children": [{"type": "t", "text": "PSMA7 inhibits the tumorigenicity of A549 human lung adenocarcinoma cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Cell Biochem (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s11010-012-1290-2"}], "href": "https://doi.org/10.1007/s11010-012-1290-2"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22584585"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22584585"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Chen-Chen Ren, Li Yang, Ling Liu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Effects of shRNA-mediated silencing of PSMA7 on cell proliferation and vascular endothelial growth factor expression via the ubiquitin-proteasome pathway in cervical cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Physiol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcp.26408"}], "href": "https://doi.org/10.1002/jcp.26408"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "29247526"}], "href": "https://pubmed.ncbi.nlm.nih.gov/29247526"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Shujing Xia, Lei Ji, Lizhong Tang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Proteasome Subunit Alpha Type 7 Promotes Proliferation and Metastasis of Gastric Cancer Through MAPK Signaling Pathway."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Dig Dis Sci (2022)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s10620-021-06903-9"}], "href": "https://doi.org/10.1007/s10620-021-06903-9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33721161"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33721161"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Xiao-Tong Hu, Wei Chen, Da Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "[High expression of proteasome subunit PSMA7 in colorectal cancer is significantly correlated with liver metastasis]."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Zhonghua Zhong Liu Za Zhi (2008)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19062718"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19062718"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Shujing Xia, Lili Zhang, Fenggan Cheng, et al. "}, {"type": "b", "children": [{"type": "t", "text": "[Expression of PSMA 7 and its effect on proliferation, invasion, migration and tumorigenesis of gastric cancer]."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nan Fang Yi Ke Da Xue Xue Bao (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.12122/j.issn.1673-4254.2019.04.02"}], "href": "https://doi.org/10.12122/j.issn.1673-4254.2019.04.02"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31068280"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31068280"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Xiangshu Xu, Meiling Pei, Ki-Yeol Kim, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Proteasome Subunit Alpha Type-7 Expression Suppresses Cutaneous Squamous Cell Carcinoma Progression by Inhibiting Cancer-associated Cytokines."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "In Vivo (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.21873/invivo.13243"}], "href": "https://doi.org/10.21873/invivo.13243"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37369480"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37369480"}]}, {"type": "r", "ref": 17, "children": [{"type": "t", "text": "Guangying Sheng, Fuyu Li, Wen Jin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Pan-caner analysis identifies PSMA7 as a targets for amplification at 20q13.33 in tumorigenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Sci Rep (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41598-024-53585-0"}], "href": "https://doi.org/10.1038/s41598-024-53585-0"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38321088"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38321088"}]}]}]}
Synonyms	C6, XAPC7, RC6-1, HSPC, HEL-S-276
Proteins	PSA7_HUMAN
NCBI Gene ID	5688
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

PSMA7 has 11,178 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 123 datasets.

Click the + buttons to view associations for PSMA7 from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

PSMA7 Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by PSMA7 gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PSMA7 gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of PSMA7 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of PSMA7 gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of PSMA7 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of PSMA7 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of PSMA7 gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	Biocarta Pathways	pathways involving PSMA7 protein from the Biocarta Pathways dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of PSMA7 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of PSMA7 gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of PSMA7 gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of PSMA7 gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of PSMA7 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of PSMA7 gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with PSMA7 protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with PSMA7 gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PSMA7 gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of PSMA7 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of PSMA7 gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations 2025	phenotypes associated with PSMA7 gene from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing PSMA7 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing PSMA7 protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with PSMA7 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with PSMA7 protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing PSMA7 protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene CNV Profiles	cell lines with high or low copy number of PSMA7 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with PSMA7 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with PSMA7 gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with PSMA7 gene/protein from the curated CTD Gene-Disease Associations dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with PSMA7 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with PSMA7 gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with PSMA7 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with PSMA7 gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	DrugBank Drug Targets	interacting drugs for PSMA7 protein from the curated DrugBank Drug Targets dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at PSMA7 gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of PSMA7 gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of PSMA7 gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing PSMA7 from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GAD High Level Gene-Disease Associations	diseases associated with PSMA7 gene in GWAS and other genetic association datasets from the GAD High Level Gene-Disease Associations dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of PSMA7 gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.