| HGNC Family | Non-coding RNAs |
| Name | Prader Willi/Angelman region RNA 1 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nThe abstract associated with citation"}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "focused on the contribution of several genetic polymorphisms (in NFKB1, PAR1, TP53, IL-1A, and UCP2) to NSCLC susceptibility; however, it did not describe or explore the function of PWAR1. As a result, none of the findings or discussions in this publication provide insight into PWAR1’s biological role or its involvement in lung cancer oncogenesis."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "Discerning the specific functions and regulatory mechanisms of PWAR1 in a carcinogenic context remains an open question. While the study identified key genetic variants impacting inflammatory response, genomic stability, and metabolism in NSCLC, the absence of any mention of PWAR1 underscores the need for additional investigations that directly target its role in cancer biology."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": ""}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Esdras E B Pereira, Antônio A C Modesto, Bruno M Fernandes, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Association between Polymorphism of Genes "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "IL-1A"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": ", "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "NFKB1"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": ", "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "PAR1"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": ", "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "TP53,"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " and "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "UCP2"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " and Susceptibility to Non-Small Cell Lung Cancer in the Brazilian Amazon."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Genes (Basel) (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/genes14020461"}], "href": "https://doi.org/10.3390/genes14020461"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36833388"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36833388"}]}]}]}
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| Synonyms | D15S227E |
| NCBI Gene ID | 145624 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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PWAR1 has 181 functional associations with biological entities spanning 2 categories (disease, phenotype or trait, cell line, cell type or tissue) extracted from 3 datasets.
Click the + buttons to view associations for PWAR1 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of PWAR1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| HuGE Navigator Gene-Phenotype Associations | phenotypes associated with PWAR1 gene by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of PWAR1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |