| Name | RBPMS antisense RNA 1 |
| Summary |
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRecent investigations have highlighted the emerging role of RBPMS‐AS1 in regulating lung cancer radiosensitivity, suggesting that this long non‐coding RNA may influence key cellular pathways that determine the response of tumor cells to radiotherapy. In particular, RBPMS‐AS1 is thought to modulate mechanisms such as DNA damage repair, apoptosis, and cell cycle progression, thereby directly affecting how lung cancer cells withstand or succumb to ionizing radiation. By altering these critical processes, RBPMS‐AS1 holds promise as a potential biomarker for predicting radiotherapy outcomes and as a therapeutic target to enhance treatment efficacy in lung cancer patients."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Chengyu Ye, Quanbing Lin, Cuiping Zheng "}, {"type": "b", "children": [{"type": "t", "text": "Overexpressed RBPMS-AS1 increased cell radiosensitivity by sponging miR-19a-3p in lung cancer cell lines (A549 and SK-MES-1) via regulating PTEN/AKT axis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Radiat Biol (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1080/09553002.2023.2181997"}], "href": "https://doi.org/10.1080/09553002.2023.2181997"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "36912590"}], "href": "https://pubmed.ncbi.nlm.nih.gov/36912590"}]}]}]}
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| NCBI Gene ID | 100128750 |
| API | |
| Download Associations | |
| Predicted Functions |
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| Co-expressed Genes |
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| Expression in Tissues and Cell Lines |
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RBPMS-AS1 has 588 functional associations with biological entities spanning 1 categories (cell line, cell type or tissue) extracted from 4 datasets.
Click the + buttons to view associations for RBPMS-AS1 from the datasets below.
If available, associations are ranked by standardized value
| Dataset | Summary | |
|---|---|---|
| CCLE Cell Line Gene CNV Profiles | cell lines with high or low copy number of RBPMS-AS1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. | |
| GTEx Tissue Gene Expression Profiles | tissues with high or low expression of RBPMS-AS1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset. | |
| GTEx Tissue Sample Gene Expression Profiles | tissue samples with high or low expression of RBPMS-AS1 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. | |
| Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles | cell lines with high or low copy number of RBPMS-AS1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset. | |