RNA5S2 Gene

HGNC Family Non-coding RNAs
Name RNA, 5S ribosomal 2
Description Predicted to be a structural constituent of ribosome. Predicted to be located in ribosome. [provided by Alliance of Genome Resources, Mar 2025]
Summary
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In the context of the diverse topics covered—from the role of mechanosensory complexes in atherogenesis to the control of cell differentiation and innate immune responses—the absence of any reference to RNA5S2 suggests that its role (if any) was not addressed in these studies. It remains possible that RNA5S2 (which, by its designation, might be related to small ribosomal or noncoding RNAs) could have functions in other cellular contexts or model systems; however, based on the current literature provided here, no contribution, molecular mechanism, or physiological role for RNA5S2 can be summarized.\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "E K Griffiths, C Krawczyk, Y Y Kong, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Stem Cell (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.stem.2012.06.008"}], "href": "https://doi.org/10.1016/j.stem.2012.06.008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23040478"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23040478"}]}, {"type": "r", "ref": 31, "children": [{"type": "t", "text": "Yan-Chuan Shi, Jackie Lau, Zhou Lin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Metab (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cmet.2013.01.006"}], "href": "https://doi.org/10.1016/j.cmet.2013.01.006"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23395170"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23395170"}]}, {"type": "r", "ref": 32, "children": [{"type": "t", "text": "Elaine Wan, Xin Yi Yeap, Shirley Dehn, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Enhanced efferocytosis of apoptotic cardiomyocytes through myeloid-epithelial-reproductive tyrosine kinase links acute inflammation resolution to cardiac repair after infarction."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Circ Res (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/CIRCRESAHA.113.301198"}], "href": "https://doi.org/10.1161/CIRCRESAHA.113.301198"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23836795"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23836795"}]}, {"type": "r", "ref": 33, "children": [{"type": "t", "text": "Susan Carpenter, Daniel Aiello, Maninjay K Atianand, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A long noncoding RNA mediates both activation and repression of immune response genes."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Science (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1126/science.1240925"}], "href": "https://doi.org/10.1126/science.1240925"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "23907535"}], "href": "https://pubmed.ncbi.nlm.nih.gov/23907535"}]}, {"type": "r", "ref": 34, "children": [{"type": "t", "text": "Jonas J Neher, Julius V Emmrich, Michael Fricker, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Phagocytosis executes delayed neuronal death after focal brain ischemia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Proc Natl Acad Sci U S A (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1073/pnas.1308679110"}], "href": "https://doi.org/10.1073/pnas.1308679110"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24101459"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24101459"}]}, {"type": "r", "ref": 35, "children": [{"type": "t", "text": "Won-Suk Chung, Laura E Clarke, Gordon X Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2013)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature12776"}], "href": "https://doi.org/10.1038/nature12776"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24270812"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24270812"}]}, {"type": "r", "ref": 36, "children": [{"type": "t", "text": "Anna Zagórska, Paqui G Través, Erin D Lew, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Diversification of TAM receptor tyrosine kinase function."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Immunol (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ni.2986"}], "href": "https://doi.org/10.1038/ni.2986"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25194421"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25194421"}]}, {"type": "r", "ref": 37, "children": [{"type": "t", "text": "Erin D Lew, Jennifer Oh, Patrick G Burrola, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Elife (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7554/eLife.03385"}], "href": "https://doi.org/10.7554/eLife.03385"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25265470"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25265470"}]}, {"type": "r", "ref": 38, "children": [{"type": "t", "text": "James Y Chen, Masanori Miyanishi, Sean K Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature16943"}], "href": "https://doi.org/10.1038/nature16943"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26863982"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26863982"}]}, {"type": "r", "ref": 39, "children": [{"type": "t", "text": "Lawrence Fourgeaud, Paqui G Través, Yusuf Tufail, et al. "}, {"type": "b", "children": [{"type": "t", "text": "TAM receptors regulate multiple features of microglial physiology."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nature17630"}], "href": "https://doi.org/10.1038/nature17630"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "27049947"}], "href": "https://pubmed.ncbi.nlm.nih.gov/27049947"}]}, {"type": "r", "ref": 40, "children": [{"type": "t", "text": "Katrin Fischer, Henry H Ruiz, Kevin Jhun, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Med (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/nm.4316"}], "href": "https://doi.org/10.1038/nm.4316"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28414329"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28414329"}]}, {"type": "r", "ref": 41, "children": [{"type": "t", "text": "Yi Zhou, Mingjian Fei, Gu Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Immunity (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.immuni.2020.01.014"}], "href": "https://doi.org/10.1016/j.immuni.2020.01.014"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32049051"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32049051"}]}, {"type": "r", "ref": 42, "children": [{"type": "t", "text": "Youtong Huang, Kaisa E Happonen, Patrick G Burrola, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Microglia use TAM receptors to detect and engulf amyloid β plaques."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Immunol (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41590-021-00913-5"}], "href": "https://doi.org/10.1038/s41590-021-00913-5"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33859405"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33859405"}]}]}]}
Synonyms RN5S2
NCBI Gene ID 100169753
API
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Predicted Functions View RNA5S2's ARCHS4 Predicted Functions.
Co-expressed Genes View RNA5S2's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View RNA5S2's ARCHS4 Predicted Functions.

Functional Associations

RNA5S2 has 107 functional associations with biological entities spanning 1 categories (cell line, cell type or tissue) extracted from 1 datasets.

Click the + buttons to view associations for RNA5S2 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of RNA5S2 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.