RNF227 Gene

Name ring finger protein 227
Description Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. [provided by Alliance of Genome Resources, Mar 2025]
NCBI Gene ID 284023
API
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Predicted Functions View RNF227's ARCHS4 Predicted Functions.
Co-expressed Genes View RNF227's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View RNF227's ARCHS4 Predicted Functions.

Functional Associations

RNF227 has 1,239 functional associations with biological entities spanning 5 categories (disease, phenotype or trait, functional term, phrase or reference, chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 12 datasets.

Click the + buttons to view associations for RNF227 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
CellMarker Gene-Cell Type Associations cell types associated with RNF227 gene from the CellMarker Gene-Cell Type Associations dataset.
CM4AI KOLF21J CRISPRi Gene Perturbation Atlas gene perturbations changing expression of RNF227 gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
DISEASES Experimental Gene-Disease Association Evidence Scores 2025 diseases associated with RNF227 gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
GO Biological Process Annotations 2025 biological processes involving RNF227 gene from the curated GO Biological Process Annotations2025 dataset.
GO Molecular Function Annotations 2025 molecular functions performed by RNF227 gene from the curated GO Molecular Function Annotations 2025 dataset.
JASPAR Predicted Human Transcription Factor Targets 2025 transcription factors regulating expression of RNF227 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.
JASPAR Predicted Mouse Transcription Factor Targets 2025 transcription factors regulating expression of RNF227 gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2025 dataset.
NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles drug perturbations changing expression of RNF227 gene from the NIBR DRUG-seq U2OS MoA Box dataset.
Rummagene Transcription Factor Associations 2026 transcription factors regulating expression of RNF227 gene from the Rummagene Transcription Factor Associations 2026 dataset.
RummaGEO Drug Perturbation Signatures drug perturbations changing expression of RNF227 gene from the RummaGEO Drug Perturbation Signatures dataset.
RummaGEO Gene Perturbation Signatures gene perturbations changing expression of RNF227 gene from the RummaGEO Gene Perturbation Signatures dataset.
TISSUES Curated Tissue Protein Expression Evidence Scores 2025 tissues with high expression of RNF227 protein from the TISSUES Curated Tissue Protein Expression Evidence Scores 2025 dataset.