RPS27A Gene

HGNC Family	S ribosomal proteins (RPS)
Name	ribosomal protein S27a
Description	Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.[provided by RefSeq, Sep 2008]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nRPS27A is expressed as part of an ubiquitin‐ribosomal fusion protein that is processed to generate free ubiquitin and the ribosomal protein RPS27A, which not only incorporates into the ribosome for canonical protein synthesis but also performs crucial extra‐ribosomal functions. Several studies have shown that RPS27A directly interacts with MDM2 via its acidic domain, thereby inhibiting MDM2‐mediated p53 ubiquitination and amplifying p53 activation under ribosomal stress and DNA damage. Moreover, p53 itself can transcriptionally up‐regulate RPS27A, positioning this protein as a stress sensor that reinforces cell cycle arrest and apoptosis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "5"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its canonical role in translation, RPS27A exerts significant influence on tumorigenesis in various cancers. In leukemia, prostate carcinoma, and cervical cancer, elevated levels of RPS27A promote cell proliferation, drive cell cycle progression, and inhibit apoptosis. Its expression can be directly up‐regulated by activated STAT3 in imatinib‑resistant chronic myeloid leukemia cells, and its interaction with oncoviral proteins such as EBV‑encoded LMP1 stabilizes these proteins to enhance oncogenic proliferation and invasion. In multiple myeloma, an RPS27A‑related transcript variant is associated with poor prognosis, further highlighting the clinical impact of its dysregulation."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "6", "end_ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nIn addition to its roles in stress signaling and oncogenesis, RPS27A is pivotal in ribosome biogenesis and the maintenance of translational competence. Its ubiquitination status—regulated by deubiquitinases such as USP16—is critical for the proper maturation of the 40S ribosomal subunit, linking ribosome assembly with active protein synthesis. RPS27A has also emerged as a modulator of DNA repair processes by interacting with histones and the E3 ligase RNF168, thereby fine‑tuning ubiquitination signaling at sites of DNA damage. Moreover, network analyses have identified RPS27A as a switch gene in neurodegenerative disorders, while altered RPS27A expression has been observed in conditions such as gastric cancer, epidermolysis bullosa, and autoimmune responses potentially triggered by infectious agents."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "18"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Yon Ko, Tanja Hahn, Hong Lu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "A novel component of the ubiquitin pathway, ubiquitin carboxyl extension protein 1 is overexpressed in prostate cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Med (2005)"}]}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "15647830"}], "href": "https://pubmed.ncbi.nlm.nih.gov/15647830"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Xiao-Xin Sun, Tiffany DeVine, Kishore B Challagundla, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M111.223651"}], "href": "https://doi.org/10.1074/jbc.M111.223651"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21561866"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21561866"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "Nagisa Nosrati, Neetu Rohit Kapoor, Vijay Kumar "}, {"type": "b", "children": [{"type": "t", "text": "DNA damage stress induces the expression of ribosomal protein S27a gene in a p53-dependent manner."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Gene (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.gene.2015.01.014"}], "href": "https://doi.org/10.1016/j.gene.2015.01.014"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25592822"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25592822"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Huai Wang, Junjie Zhao, Jian Yang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "PICT1 is critical for regulating the Rps27a-Mdm2-p53 pathway by microtubule polymerization inhibitor against cervical cancer."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochim Biophys Acta Mol Cell Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbamcr.2021.119084"}], "href": "https://doi.org/10.1016/j.bbamcr.2021.119084"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34166715"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34166715"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Matthew John Eastham, Andria Pelava, Graeme Raymond Wells, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RPS27a and RPL40, Which Are Produced as Ubiquitin Fusion Proteins, Are Not Essential for p53 Signalling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biomolecules (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/biom13060898"}], "href": "https://doi.org/10.3390/biom13060898"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37371478"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37371478"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Houcai Wang, Jing Yu, Lixia Zhang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RPS27a promotes proliferation, regulates cell cycle progression and inhibits apoptosis of leukemia cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2014.03.086"}], "href": "https://doi.org/10.1016/j.bbrc.2014.03.086"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24680683"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24680683"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Houcai Wang, Bingqian Xie, Yuanyuan Kong, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Oncotarget (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/oncotarget.7888"}], "href": "https://doi.org/10.18632/oncotarget.7888"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "26942564"}], "href": "https://pubmed.ncbi.nlm.nih.gov/26942564"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Seung-Woo Hong, Seung-Mi Kim, Dong-Hoon Jin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "RPS27a enhances EBV-encoded LMP1-mediated proliferation and invasion by stabilizing of LMP1."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2017.07.105"}], "href": "https://doi.org/10.1016/j.bbrc.2017.07.105"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28735865"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28735865"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Rui He, Nan Yang, Pengyu Zhang, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Interactions of antisera to different Chlamydia and Chlamydophila species with the ribosomal protein RPS27a correlate with impaired protein synthesis in a human choroid plexus papilloma cell line."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Immunol Res (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1007/s12026-017-8952-9"}], "href": "https://doi.org/10.1007/s12026-017-8952-9"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28913776"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28913776"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Julia Knaup, Thomas Verwanger, Christina Gruber, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Epidermolysis bullosa - a group of skin diseases with different causes but commonalities in gene expression."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Exp Dermatol (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1600-0625.2012.01519.x"}], "href": "https://doi.org/10.1111/j.1600-0625.2012.01519.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22716248"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22716248"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Hyun-Jung Kim, Antoni Barrientos "}, {"type": "b", "children": [{"type": "t", "text": "MTG1 couples mitoribosome large subunit assembly with intersubunit bridge formation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nucleic Acids Res (2018)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1093/nar/gky672"}], "href": "https://doi.org/10.1093/nar/gky672"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30085276"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30085276"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Christian Montellese, Jasmin van den Heuvel, Caroline Ashiono, et al. "}, {"type": "b", "children": [{"type": "t", "text": "USP16 counteracts mono-ubiquitination of RPS27a and promotes maturation of the 40S ribosomal subunit."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Elife (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.7554/eLife.54435"}], "href": "https://doi.org/10.7554/eLife.54435"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32129764"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32129764"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Emanuele Salvatore Scarpa, Filippo Tasini, Rita Crinelli, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The Ubiquitin Gene Expression Pattern and Sensitivity to "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "UBB"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " and "}, {"type": "a", "children": [{"type": "t", "text": "i"}], "href": "i"}, {"type": "t", "text": "UBC"}, {"type": "a", "children": [{"type": "t", "text": "/i"}], "href": "/i"}, {"type": "t", "text": " Knockdown Differentiate Primary 23132/87 and Metastatic MKN45 Gastric Cancer Cells."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Int J Mol Sci (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.3390/ijms21155435"}], "href": "https://doi.org/10.3390/ijms21155435"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32751694"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32751694"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Nasibeh Khayer, Mehdi Mirzaie, Sayed-Amir Marashi, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "UBA80 and UBA52 fine-tune RNF168-dependent histone ubiquitination and DNA repair."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2023)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jbc.2023.105043"}], "href": "https://doi.org/10.1016/j.jbc.2023.105043"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "37451480"}], "href": "https://pubmed.ncbi.nlm.nih.gov/37451480"}]}, {"type": "r", "ref": 18, "children": [{"type": "t", "text": "Vinoth Prasanna Gunasekaran, Mathan Ganeshan "}, {"type": "b", "children": [{"type": "t", "text": "Inverse correlation of ribosomal protein S27A and multifunctional protein YB-1 in hepatocellular carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Biochem (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.clinbiochem.2014.05.004"}], "href": "https://doi.org/10.1016/j.clinbiochem.2014.05.004"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24833360"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24833360"}]}]}]}
Synonyms	HEL112, UBCEP1, S27A, UBA80, CEP80, UBCEP80, UBC
Proteins	RS27A_HUMAN
NCBI Gene ID	6233
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

RPS27A has 19,206 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 118 datasets.

Click the + buttons to view associations for RPS27A from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

RPS27A Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by RPS27A gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of RPS27A gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of RPS27A gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	tissue samples with high or low expression of RPS27A gene relative to other tissue samples from the Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of RPS27A gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of RPS27A gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of RPS27A gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of RPS27A gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of RPS27A gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	small molecule perturbations changing expression of RPS27A gene from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of RPS27A gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of RPS27A gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with RPS27A protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with RPS27A gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of RPS27A gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of RPS27A gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of RPS27A gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	gene perturbations changing expression of RPS27A gene from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of RPS27A gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing RPS27A protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing RPS27A protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with RPS27A protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with RPS27A protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	CORUM Protein Complexes	protein complexs containing RPS27A protein from the CORUM Protein Complexes dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with RPS27A gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Chemical Interactions	chemicals interacting with RPS27A gene/protein from the curated CTD Gene-Chemical Interactions dataset.
	CTD Gene-Disease Associations	diseases associated with RPS27A gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of RPS27A protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DGIdb Drug Targets 2026	interacting drugs for RPS27A protein from the DGIdb Drug Targets 2026 dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving RPS27A gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with RPS27A gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with RPS27A gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with RPS27A gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with RPS27A gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at RPS27A gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of RPS27A gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of RPS27A gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing RPS27A from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of RPS27A gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with RPS27A gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.