{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nIn a study focused on hepatocellular carcinoma (HCC), SACS‑AS1 was identified as one of nine long non‑coding RNAs (lncRNAs) that together form a prognostic signature for the disease. The research utilized RNA sequencing data from The Cancer Genome Atlas to examine lncRNA expression profiles in HCC patients. SACS‑AS1, as part of this 9‑lncRNA model, was found to contribute to the predictive ability of the signature, which was developed via multivariate Cox regression analysis. Although the precise biological mechanisms of SACS‑AS1 in HCC progression were not detailed, its differential expression is associated with patient prognosis, suggesting that it may serve as a valuable biomarker for risk assessment and personalized management in HCC."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Benyuan Deng, Min Yang, Ming Wang, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Development and validation of 9-long Non-coding RNA signature to predicting survival in hepatocellular carcinoma."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Medicine (Baltimore) (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/MD.0000000000020422"}], "href": "https://doi.org/10.1097/MD.0000000000020422"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32481346"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32481346"}]}]}]}