SAR1B Gene

HGNC Family	Ras small GTPases superfamily
Name	secretion associated, Ras related GTPase 1B
Description	The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
Summary	{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nSAR1B is an essential small GTPase that initiates the assembly of COPII‐coated vesicles from the endoplasmic reticulum, a process critical for the transport of large lipid‐cargos such as chylomicrons. Mutations in SAR1B disrupt this selective recruitment and result in severe fat malabsorption syndromes—commonly known as chylomicron retention or Anderson disease—underscoring its pivotal role in intestinal lipid export and overall nutrient absorption."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "1", "end_ref": "6"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nBeyond its canonical role in vesicle formation, SAR1B exhibits unique biochemical characteristics that facilitate the efficient packaging and selective secretion of large apoB-containing lipoproteins. Its specific interactions—with components such as SEC23A of the COPII coat—and its regulation by dietary lipids enable coordinated secretion processes in both the intestine and liver, where SAR1B also modulates cholesterol synthesis. Such mechanistic insights highlight how SAR1B’s function diverges from its paralog SAR1A, which in some contexts antagonizes lipoprotein secretion, thereby emphasizing the dosage-sensitive and specialized nature of SAR1B in lipid homeostasis."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "7", "end_ref": "11"}]}, {"type": "t", "text": "\n"}]}, {"type": "t", "text": "\n\n"}, {"type": "p", "children": [{"type": "t", "text": "\nRecent studies have further expanded the functional spectrum of SAR1B. Notably, SAR1B can act as a sensor for intracellular leucine levels, modulating mTORC1 signaling by binding leucine and altering its interaction with regulatory proteins. In addition, genetic models in which SAR1B is deleted or mutated have revealed downstream effects on fatty acid oxidation, lipogenesis, oxidative balance, and inflammation—demonstrating that SAR1B not only governs vesicular trafficking but also influences broader aspects of lipid metabolism. Moreover, emerging genetic associations even hint at a potential link between SAR1B variants and neurodegenerative disorders. Together, these findings indicate that the specialized activities of SAR1B are fundamental to both lipid transport and cellular metabolic regulation, with significant implications for disease."}, {"type": "fg", "children": [{"type": "fg_fs", "start_ref": "12", "end_ref": "17"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Bethan Jones, Emma L Jones, Stephanie A Bonney, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nat Genet (2003)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/ng1145"}], "href": "https://doi.org/10.1038/ng1145"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "12692552"}], "href": "https://pubmed.ncbi.nlm.nih.gov/12692552"}]}, {"type": "r", "ref": 2, "children": [{"type": "t", "text": "Mathilde Charcosset, Agnès Sassolas, Noël Peretti, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Anderson or chylomicron retention disease: molecular impact of five mutations in the SAR1B gene on the structure and the functionality of Sar1b protein."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Mol Genet Metab (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.ymgme.2007.08.120"}], "href": "https://doi.org/10.1016/j.ymgme.2007.08.120"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "17945526"}], "href": "https://pubmed.ncbi.nlm.nih.gov/17945526"}]}, {"type": "r", "ref": 3, "children": [{"type": "t", "text": "M Silvain, D Bligny, T Aparicio, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Anderson's disease (chylomicron retention disease): a new mutation in the SARA2 gene associated with muscular and cardiac abnormalities."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Clin Genet (2008)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1111/j.1399-0004.2008.01069.x"}], "href": "https://doi.org/10.1111/j.1399-0004.2008.01069.x"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "18786134"}], "href": "https://pubmed.ncbi.nlm.nih.gov/18786134"}]}, {"type": "r", "ref": 4, "children": [{"type": "t", "text": "Angelo B Cefalù, Pier L Calvo, Davide Noto, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Variable phenotypic expression of chylomicron retention disease in a kindred carrying a mutation of the Sara2 gene."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Metabolism (2010)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.metabol.2009.07.042"}], "href": "https://doi.org/10.1016/j.metabol.2009.07.042"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "19846172"}], "href": "https://pubmed.ncbi.nlm.nih.gov/19846172"}]}, {"type": "r", "ref": 5, "children": [{"type": "t", "text": "Alain Théophile Sané, Ernest Seidman, Noel Peretti, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Understanding Chylomicron Retention Disease Through Sar1b Gtpase Gene Disruption: Insight From Cell Culture."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arterioscler Thromb Vasc Biol (2017)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/ATVBAHA.117.310121"}], "href": "https://doi.org/10.1161/ATVBAHA.117.310121"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "28982670"}], "href": "https://pubmed.ncbi.nlm.nih.gov/28982670"}]}, {"type": "r", "ref": 6, "children": [{"type": "t", "text": "Emile Levy, Pierre Poinsot, Schohraya Spahis "}, {"type": "b", "children": [{"type": "t", "text": "Chylomicron retention disease: genetics, biochemistry, and clinical spectrum."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Curr Opin Lipidol (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1097/MOL.0000000000000578"}], "href": "https://doi.org/10.1097/MOL.0000000000000578"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "30640893"}], "href": "https://pubmed.ncbi.nlm.nih.gov/30640893"}]}, {"type": "r", "ref": 7, "children": [{"type": "t", "text": "Emile Levy, Elodie Harmel, Martine Laville, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Expression of Sar1b enhances chylomicron assembly and key components of the coat protein complex II system driving vesicle budding."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Arterioscler Thromb Vasc Biol (2011)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1161/ATVBAHA.111.233908"}], "href": "https://doi.org/10.1161/ATVBAHA.111.233908"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "21836065"}], "href": "https://pubmed.ncbi.nlm.nih.gov/21836065"}]}, {"type": "r", "ref": 8, "children": [{"type": "t", "text": "Andrew F Loftus, Vivian L Hsieh, Raghuveer Parthasarathy "}, {"type": "b", "children": [{"type": "t", "text": "Modulation of membrane rigidity by the human vesicle trafficking proteins Sar1A and Sar1B."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Biochem Biophys Res Commun (2012)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.bbrc.2012.08.131"}], "href": "https://doi.org/10.1016/j.bbrc.2012.08.131"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "22974979"}], "href": "https://pubmed.ncbi.nlm.nih.gov/22974979"}]}, {"type": "r", "ref": 9, "children": [{"type": "t", "text": "Lee G D Fryer, Bethan Jones, Emma J Duncan, et al. "}, {"type": "b", "children": [{"type": "t", "text": "The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2014)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.M113.479980"}], "href": "https://doi.org/10.1074/jbc.M113.479980"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "24338480"}], "href": "https://pubmed.ncbi.nlm.nih.gov/24338480"}]}, {"type": "r", "ref": 10, "children": [{"type": "t", "text": "Alain Sané, Ernest Seidman, Schohraya Spahis, et al. "}, {"type": "b", "children": [{"type": "t", "text": "New Insights In Intestinal Sar1B GTPase Regulation and Role in Cholesterol Homeostasis."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Cell Biochem (2015)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1002/jcb.25177"}], "href": "https://doi.org/10.1002/jcb.25177"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25826777"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25826777"}]}, {"type": "r", "ref": 11, "children": [{"type": "t", "text": "David B Melville, Sean Studer, Randy Schekman "}, {"type": "b", "children": [{"type": "t", "text": "Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Biol Chem (2020)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1074/jbc.RA120.012964"}], "href": "https://doi.org/10.1074/jbc.RA120.012964"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "32358066"}], "href": "https://pubmed.ncbi.nlm.nih.gov/32358066"}]}, {"type": "r", "ref": 12, "children": [{"type": "t", "text": "Alain Sané, Lena Ahmarani, Edgard Delvin, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Lipid Res (2019)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1194/jlr.RA119000119"}], "href": "https://doi.org/10.1194/jlr.RA119000119"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "31409740"}], "href": "https://pubmed.ncbi.nlm.nih.gov/31409740"}]}, {"type": "r", "ref": 13, "children": [{"type": "t", "text": "Xiao Wang, Huimin Wang, Bolin Xu, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Cell Metab (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.cmet.2020.10.020"}], "href": "https://doi.org/10.1016/j.cmet.2020.10.020"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33186557"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33186557"}]}, {"type": "r", "ref": 14, "children": [{"type": "t", "text": "Nickolas Auclair, Alain T Sané, Lena Ahmarani, et al. "}, {"type": "b", "children": [{"type": "t", "text": "Sar1b mutant mice recapitulate gastrointestinal abnormalities associated with chylomicron retention disease."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Lipid Res (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jlr.2021.100085"}], "href": "https://doi.org/10.1016/j.jlr.2021.100085"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "33964306"}], "href": "https://pubmed.ncbi.nlm.nih.gov/33964306"}]}, {"type": "r", "ref": 15, "children": [{"type": "t", "text": "Jie Chen, Yuhui Ou, Rong Luo, et al. "}, {"type": "b", "children": [{"type": "t", "text": "SAR1B senses leucine levels to regulate mTORC1 signalling."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Nature (2021)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1038/s41586-021-03768-w"}], "href": "https://doi.org/10.1038/s41586-021-03768-w"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "34290409"}], "href": "https://pubmed.ncbi.nlm.nih.gov/34290409"}]}, {"type": "r", "ref": 16, "children": [{"type": "t", "text": "Vi T Tang, Jie Xiang, Zhimin Chen, et al. 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"}, {"type": "b", "children": [{"type": "t", "text": "Genetic polymorphisms of lipid metabolism gene SAR1 homolog B and the risk of Alzheimer's disease and vascular dementia."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "J Formos Med Assoc (2016)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.1016/j.jfma.2015.01.008"}], "href": "https://doi.org/10.1016/j.jfma.2015.01.008"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "25703997"}], "href": "https://pubmed.ncbi.nlm.nih.gov/25703997"}]}]}]}
Synonyms	CMRD, ANDD, SARA2, GTBPB
Proteins	SAR1B_HUMAN
NCBI Gene ID	51128
API
Download Associations
Predicted Functions
Co-expressed Genes
Expression in Tissues and Cell Lines

Functional Associations

SAR1B has 7,360 functional associations with biological entities spanning 8 categories (molecular profile, organism, disease, phenotype or trait, chemical, functional term, phrase or reference, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 115 datasets.

Click the + buttons to view associations for SAR1B from the datasets below.

If available, associations are ranked by standardized value

Harmonizome 3.0

SAR1B Gene

Functional Associations

Please acknowledge the Harmonizome in your publications by citing the following reference(s):

	Dataset	Summary
	Achilles Cell Line Gene Essentiality Profiles	cell lines with fitness changed by SAR1B gene knockdown relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.
	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SAR1B gene relative to other tissues from the Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	tissues with high or low expression of SAR1B gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	tissue samples with high or low expression of SAR1B gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray dataset.
	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	tissue samples with high or low expression of SAR1B gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	tissues with high or low expression of SAR1B gene relative to other tissues from the Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles dataset.
	BioGPS Cell Line Gene Expression Profiles	cell lines with high or low expression of SAR1B gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset.
	BioGPS Human Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SAR1B gene relative to other cell types and tissues from the BioGPS Human Cell Type and Tissue Gene Expression Profiles dataset.
	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	cell types and tissues with high or low expression of SAR1B gene relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset.
	CCLE Cell Line Gene CNV Profiles	cell lines with high or low copy number of SAR1B gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
	CCLE Cell Line Gene Expression Profiles	cell lines with high or low expression of SAR1B gene relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.
	CCLE Cell Line Proteomics	Cell lines associated with SAR1B protein from the CCLE Cell Line Proteomics dataset.
	CellMarker Gene-Cell Type Associations	cell types associated with SAR1B gene from the CellMarker Gene-Cell Type Associations dataset.
	ChEA Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SAR1B gene from the CHEA Transcription Factor Binding Site Profiles dataset.
	ChEA Transcription Factor Targets	transcription factors binding the promoter of SAR1B gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.
	ChEA Transcription Factor Targets 2022	transcription factors binding the promoter of SAR1B gene in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.
	ClinVar Gene-Phenotype Associations	phenotypes associated with SAR1B gene from the curated ClinVar Gene-Phenotype Associations dataset.
	CMAP Signatures of Differentially Expressed Genes for Small Molecules	small molecule perturbations changing expression of SAR1B gene from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores	cellular components containing SAR1B protein from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	cellular components containing SAR1B protein from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores	cellular components co-occuring with SAR1B protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	cellular components co-occuring with SAR1B protein in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
	COSMIC Cell Line Gene Mutation Profiles	cell lines with SAR1B gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset.
	CTD Gene-Disease Associations	diseases associated with SAR1B gene/protein from the curated CTD Gene-Disease Associations dataset.
	DeepCoverMOA Drug Mechanisms of Action	small molecule perturbations with high or low expression of SAR1B protein relative to other small molecule perturbations from the DeepCoverMOA Drug Mechanisms of Action dataset.
	DepMap CRISPR Gene Dependency	cell lines with fitness changed by SAR1B gene knockdown relative to other cell lines from the DepMap CRISPR Gene Dependency dataset.
	DISEASES Curated Gene-Disease Association Evidence Scores 2025	diseases involving SAR1B gene from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	diseases associated with SAR1B gene in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores	diseases co-occuring with SAR1B gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.
	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	diseases co-occuring with SAR1B gene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
	DisGeNET Gene-Disease Associations	diseases associated with SAR1B gene in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
	DisGeNET Gene-Phenotype Associations	phenotypes associated with SAR1B gene in GWAS and other genetic association datasets from the DisGeNET Gene-Phenoptype Associations dataset.
	DrugBank Drug Targets	interacting drugs for SAR1B protein from the curated DrugBank Drug Targets dataset.
	ENCODE Histone Modification Site Profiles	histone modification site profiles with high histone modification abundance at SAR1B gene from the ENCODE Histone Modification Site Profiles dataset.
	ENCODE Transcription Factor Binding Site Profiles	transcription factor binding site profiles with transcription factor binding evidence at the promoter of SAR1B gene from the ENCODE Transcription Factor Binding Site Profiles dataset.
	ENCODE Transcription Factor Targets	transcription factors binding the promoter of SAR1B gene in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.
	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	PubMedIDs of publications reporting gene signatures containing SAR1B from the ESCAPE Omics Signatures of Genes and Proteins for Stem Cells dataset.
	GDSC Cell Line Gene Expression Profiles	cell lines with high or low expression of SAR1B gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
	GeneRIF Biological Term Annotations	biological terms co-occuring with SAR1B gene in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
	GeneSigDB Published Gene Signatures	PubMedIDs of publications reporting gene signatures containing SAR1B from the GeneSigDB Published Gene Signatures dataset.