SH3BP5-AS1 Gene

Name SH3BP5 antisense RNA 1
Summary
{"type": "root", "children": [{"type": "p", "children": [{"type": "t", "text": "\nLong noncoding RNAs have emerged as pivotal players in the development and progression of hepatocellular carcinoma (HCC). In this context, SH3BP5‑AS1 is being evaluated for its contribution to HCC carcinogenesis. Although the study primarily outlines the objective to uncover the function and mechanism of SH3BP5‑AS1, its inclusion underscores a potential role in modulating cellular pathways that may drive tumor initiation and progression. This investigation raises the possibility that SH3BP5‑AS1 could serve as a novel biomarker or therapeutic target in HCC management, reflecting a growing interest in lncRNAs as key regulatory molecules in cancer biology."}, {"type": "fg", "children": [{"type": "fg_f", "ref": "1"}]}, {"type": "t", "text": "\n"}]}, {"type": "rg", "children": [{"type": "r", "ref": 1, "children": [{"type": "t", "text": "Xinyang Zhao, Xinfeng Zhu, Chaowen Xiao, et al. "}, {"type": "b", "children": [{"type": "t", "text": "LncRNA SH3BP5-AS1 promotes hepatocellular carcinoma progression by sponging miR-6838-5p and activation of PTPN4."}]}, {"type": "t", "text": " "}, {"type": "i", "children": [{"type": "t", "text": "Aging (Albany NY) (2024)"}]}, {"type": "t", "text": " DOI: "}, {"type": "a", "children": [{"type": "t", "text": "10.18632/aging.205811"}], "href": "https://doi.org/10.18632/aging.205811"}, {"type": "t", "text": " PMID: "}, {"type": "a", "children": [{"type": "t", "text": "38761175"}], "href": "https://pubmed.ncbi.nlm.nih.gov/38761175"}]}]}]}
NCBI Gene ID 100505696
API
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Predicted Functions View SH3BP5-AS1's ARCHS4 Predicted Functions.
Co-expressed Genes View SH3BP5-AS1's ARCHS4 Predicted Functions.
Expression in Tissues and Cell Lines View SH3BP5-AS1's ARCHS4 Predicted Functions.

Functional Associations

SH3BP5-AS1 has 665 functional associations with biological entities spanning 2 categories (chemical, cell line, cell type or tissue) extracted from 8 datasets.

Click the + buttons to view associations for SH3BP5-AS1 from the datasets below.

If available, associations are ranked by standardized value

Dataset Summary
Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq tissue samples with high or low expression of SH3BP5-AS1 gene relative to other tissue samples from the Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq dataset.
CCLE Cell Line Gene CNV Profiles cell lines with high or low copy number of SH3BP5-AS1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset.
CellMarker Gene-Cell Type Associations cell types associated with SH3BP5-AS1 gene from the CellMarker Gene-Cell Type Associations dataset.
COSMIC Cell Line Gene CNV Profiles cell lines with high or low copy number of SH3BP5-AS1 gene relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.
GEO Signatures of Differentially Expressed Genes for Small Molecules small molecule perturbations changing expression of SH3BP5-AS1 gene from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.
GTEx Tissue Gene Expression Profiles tissues with high or low expression of SH3BP5-AS1 gene relative to other tissues from the GTEx Tissue Gene Expression Profiles dataset.
GTEx Tissue Sample Gene Expression Profiles tissue samples with high or low expression of SH3BP5-AS1 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset.
Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles cell lines with high or low copy number of SH3BP5-AS1 gene relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.